317806-90-9

Basic information

• Product Name: 4-(2-Morpholinoethoxy)naphthalen-1-amine
• Synonyms: 4-(2-Morpholinoethoxy)naphthalen-1-amine;4-(2-morpholin-4-ylethoxy)-1-naphthylamine;4-(2-Morpholin-4-yl-ethoxy)-naphthalen-1-ylaMine;1-NaphthalenaMine, 4-[2-(4-Morpholinyl)ethoxy]-;4-[2-(Morpholin-4-yl)ethoxy]naphthalen-1-amine
• CAS NO: 317806-90-9
• Molecular Formula: C₁₆H₂₀N₂O₂
• Molecular Weight: 272.3422
• Mol File: 317806-90-9.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 477.484 °C at 760 mmHg
• Flash Point: 242.574 °C
• Appearance: /
• Density: 1.179 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.622
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(2-Morpholinoethoxy)naphthalen-1-amine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Morpholinoethoxy)naphthalen-1-amine(317806-90-9)
• EPA Substance Registry System: 4-(2-Morpholinoethoxy)naphthalen-1-amine(317806-90-9)

Safety Data

• Hazardous Substances Data: 317806-90-9(Hazardous Substances Data)

Usage

General Description

4-(2-Morpholinoethoxy)naphthalen-1-amine is a chemical compound that consists of a naphthalene ring with an amine group at the 1-position and a morpholinoethoxy moiety at the 4-position. 4-(2-Morpholinoethoxy)naphthalen-1-amine is often used as a building block in organic synthesis and can be employed in the production of various pharmaceuticals, dyes, and other organic compounds. It has potential applications in medicinal chemistry and drug development due to its unique structure and reactivity. Additionally, it may also have applications in materials science and polymer synthesis due to its versatile chemical properties. Overall, 4-(2-Morpholinoethoxy)naphthalen-1-amine is a valuable chemical compound with a wide range of potential uses in various fields of science and industry.

InChI:InChI=1/C16H20N2O2/c17-15-5-6-16(14-4-2-1-3-13(14)15)20-12-9-18-7-10-19-11-8-18/h1-6H,7-12,17H2

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 3647-69-6 4-(2-chloroethyl)morpholine hydrochride 
• 5959-56-8 4-amino-1-naphthol hydrochloride 
• 285984-22-7 tert-butyl 4-hydroxynaphthalen-1-ylcarbamate 
• 317806-88-5 4-nitro-1-(2-morpholinethoxy)naphthalene 
• 285984-35-2 [4-(2-morpholin-4-yl-ethoxy)naphthalen-1-yl]carbamic acid tert-butyl ester 
• 2834-90-4 4-amino-1-naphthol 

Downstream Products

• 489432-47-5 4-(3-tert-butyl-5-{3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-ureido}-pyrazol-1-yl)-benzoic acid 
• 874131-47-2 3-bromo-N-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-benzamide 
• 285983-48-4 BIRB-796 
• 848148-18-5 2-(5-tert-butyl-2-m-tolyl-2H-pyrazol-3-yl)-N-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-2-oxo-acetamide 
• 476010-09-0 1-[5-tert-butyl-2-(2-hydroxy-4-methyl-phenyl)-2H-pyrazol-3-yl]-3-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-urea 
• 848144-64-9 2-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-N-[4-(2-morpholin-4-yl-ethoxy)-naphthalen-1-yl]-2-oxo-acetamide 
• 850312-03-7 1-(5-tert-butyl-2-(3-iodo-4-methylphenyl)-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naphthalen-1-yl]urea 
• 611168-85-5 1-[2-(3-nitrophenyl)-5-tert-butyl-2H-pyrazol-3-yl]-3-[4-(2-morpholin-4-yl-ethoxy)naphthalen-1-yl]-urea 

Relevant articles and documents

1,4-DISUBSTITUTED NAPHTALENES AS INHIBITORS OF P38 MAP KINASE

In general, the present invention relates to compounds capable of inhibiting P38, methods for inhibiting P38 in vivo or in vitro, diagnostics for determining activity in the treatment of P38 and/or cytokine-associated conditions and methods for treating c

UREA DERIVATIVES AS KINASE MODULATORS

The invention provides methods and compositions for treating conditions mediated by various kinases wherein derivatives of urea compounds are employed. The invention also provides methods of using the compounds and/or compositions in the treatment of a variety of diseases and unwanted conditions in subjects.

1,4-Benzofused urea compounds useful in treating cytokine mediated diseases

Disclosed are 1,4-disubstituted benzo-fused urea compounds of formula (I): wherein Ar, X, A, L, and Q of formula(I) are defined herein. The compounds inhibit production of cytokines involved in inflammatory processes and are thus useful for treating diseases and pathological conditions involving inflammation such as chronic inflammatory disease. Also disclosed are processes for preparing these compounds and pharmaceutical compositions comprising these compounds.