318284-20-7

Basic information

• Product Name: Ethanone, 1-(2-pyrimidinyl)-, oxime, (1Z)- (9CI)
• Synonyms: Ethanone, 1-(2-pyrimidinyl)-, oxime, (1Z)- (9CI)
• CAS NO: 318284-20-7
• Molecular Formula: C6H7N3O
• Molecular Weight: 137.13928
• Product Categories: PYRIMIDINE
• Mol File: 318284-20-7.mol

Chemical Properties

• Boiling Point: 327.7±25.0 °C(Predicted)
• Appearance: /
• Density: 1.23±0.1 g/cm3(Predicted)
• PKA: 9.20±0.10(Predicted)
• CAS DataBase Reference: Ethanone, 1-(2-pyrimidinyl)-, oxime, (1Z)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 1-(2-pyrimidinyl)-, oxime, (1Z)- (9CI)(318284-20-7)
• EPA Substance Registry System: Ethanone, 1-(2-pyrimidinyl)-, oxime, (1Z)- (9CI)(318284-20-7)

Safety Data

• Hazardous Substances Data: 318284-20-7(Hazardous Substances Data)

Upstream product

• 53342-27-1 2-acetylpyrimidine 
• 14080-23-0 2-cyanopyrimidine 

Relevant articles and documents

S-6-METH0XY-2- (2- (3- (PYRIMID-2-YL) IS0XAZ0L-5-YL) PYRROLIDIN-1-YL) -4- (5-METHYL-IH-PYRAZOL-S-YLAMINO) PYRIMIDINE AND POLYMORPHIC FORMS THEREOF AS MODULATORS OF THE INSULIN-LIKE GROWTH

There is provided novel pyrimidine derivatives of formula (I) or pharmaceutically acceptable salsts thereof, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

Metal ion chelates of lipophilic alkyl diazinyl ketoximes as hydrolytic catalysts

A series of lipophilic dodecyl hetaryl ketoximes (hetaryl = pyridin-2-yl, pyridazin-3-yl, pyrimidin-2-yl, pyrimidin-4-yl, pyrazin-2-yl as well as their methyl hetaryl homologues was synthesized and hydrolytic activity of their chelates with Co2+, Ni2+, Cu2+ and Zn2+ in a micellar matrix of hexadecyltrimethylammonium bromide or in homogeneous aqueous solutions was investigated using 4-nitrophenyl acetate, 4-nitrophenyl hexanoate and 4-nitrophenyl diphenyl phosphate as model substrates. While Co2+ and Cu2+ chelates are almost inactive, those of Ni2+ and Zn2+ exhibit considerable activity. None of the studied chelates promotes hydrolysis of the used phosphate. The effective species are chelates of the metal : ligand stoichiometry 1 : 3 and 1 : 1 with Ni2+ and Zn2+, respectively, when the ester cleavage proceeds in the micellar matrix. The 1 : 2 stoichiometry was found in aqueous solutions of Ni2+ and Zn2+ chelates of methyl ketoximes.