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4,7-Dichloro benzothiophene is a chemical compound belonging to the class of benzothiophenes, which are heterocyclic aromatic compounds. It is a highly chlorinated derivative of benzothiophene, featuring two chlorine atoms attached to the 4th and 7th positions of the benzene ring. This unique structure and reactivity make it a versatile building block in organic synthesis and a promising intermediate in the synthesis of pharmaceuticals and agrochemicals.

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  • 318463-07-9 Structure
  • Basic information

    1. Product Name: 4,7-Dichloro benzothiophene
    2. Synonyms: 4,7-Dichloro benzothiophene;4,7-dichloro-1-benzothiophene;4,7-Dichlorobenzo[b]thiophene
    3. CAS NO:318463-07-9
    4. Molecular Formula: C8H4Cl2S
    5. Molecular Weight: 203.08836
    6. EINECS: N/A
    7. Product Categories: Heterocycle-oher series
    8. Mol File: 318463-07-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 294.8 °C at 760 mmHg
    3. Flash Point: 174.7 °C
    4. Appearance: /
    5. Density: 1.483 g/cm3
    6. Vapor Pressure: 0.0028mmHg at 25°C
    7. Refractive Index: 1.688
    8. Storage Temp.: 2-8°C
    9. Solubility: N/A
    10. CAS DataBase Reference: 4,7-Dichloro benzothiophene(CAS DataBase Reference)
    11. NIST Chemistry Reference: 4,7-Dichloro benzothiophene(318463-07-9)
    12. EPA Substance Registry System: 4,7-Dichloro benzothiophene(318463-07-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 318463-07-9(Hazardous Substances Data)

318463-07-9 Usage

Uses

Used in Pharmaceutical Industry:
4,7-Dichloro benzothiophene is used as an intermediate in the synthesis of various pharmaceuticals for its unique structure and reactivity, contributing to the development of new drugs with diverse therapeutic properties.
Used in Agrochemical Industry:
4,7-Dichloro benzothiophene is used as an intermediate in the synthesis of agrochemicals, such as pesticides and herbicides, due to its potential to enhance the effectiveness and selectivity of these compounds in agricultural applications.
Used in Material Science:
4,7-Dichloro benzothiophene is used as a starting material for the preparation of various functionalized derivatives with diverse properties, contributing to the development of new materials with potential applications in various industries, including electronics, coatings, and plastics.
Used in Organic Synthesis:
4,7-Dichloro benzothiophene is used as a versatile building block in organic synthesis, enabling the creation of a wide range of chemical compounds with different functionalities and applications.
Used in Environmental Research:
4,7-Dichloro benzothiophene has been investigated for its potential biological activities and as a potential environmental contaminant due to its use in industrial processes, providing valuable insights into its impact on ecosystems and human health.

Check Digit Verification of cas no

The CAS Registry Mumber 318463-07-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,1,8,4,6 and 3 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 318463-07:
(8*3)+(7*1)+(6*8)+(5*4)+(4*6)+(3*3)+(2*0)+(1*7)=139
139 % 10 = 9
So 318463-07-9 is a valid CAS Registry Number.
InChI:InChI=1/C8H4Cl2S/c9-6-1-2-7(10)8-5(6)3-4-11-8/h1-4H

318463-07-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4,7-dichloro-1-benzothiophene

1.2 Other means of identification

Product number -
Other names 4,7-Dichlorobenzo[b]thiophene

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:318463-07-9 SDS

318463-07-9Downstream Products

318463-07-9Relevant articles and documents

Unexpected formation of 4,7-dihalobenzo[b]thiophenes using Ohira-Bestmann reagent and reactivity of the halogen-substituted benzo[b]thiophenes in Suzuki-Miyaura coupling with phenylboronic acid

Toyota, Kozo,Mutoh, Hirotaka,Kishi, Hiroki,Mikami, Shinichi,Tanaka, Hiroki,Yoshida, Shuhei,Naganuma, Daisuke

, p. 1355 - 1374 (2019/12/23)

Reaction of 2-(1-adamantylsulfanyl)-3,6-dihalobenzaldehydes with Ohira-Bestmann reagent gave 4,7-dihalobenzo[b]thiophenes along with normal alkyne products. Nine types of 4,7-dihalobenzo[b]thiophenes bearing chlorine, bromine, or iodine atoms, were prepared by this method. Regioselectivity in Suzuki-Miyaura cross coupling reactions of the 4,7-dihalobenzo[b]thiophenes with PhB(OH)2 was also studied.

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