324570-26-5

Basic information

• Product Name: 4-(3-METHOXY-PHENYL)-3-OXO-BUTYRIC ACID ETHYL ESTER
• Synonyms: 4-(3-METHOXY-PHENYL)-3-OXO-BUTYRIC ACID ETHYL ESTER;3-Methoxy-b-oxo-benzenebutanoic acid ethyl ester;Ethyl 4-(3-Methoxyphenyl)-3-oxobutanoate
• CAS NO: 324570-26-5
• Molecular Formula: C₁₃H₁₆O₄
• Molecular Weight: 236.26
• Product Categories: pharmacetical
• Mol File: 324570-26-5.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(3-METHOXY-PHENYL)-3-OXO-BUTYRIC ACID ETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3-METHOXY-PHENYL)-3-OXO-BUTYRIC ACID ETHYL ESTER(324570-26-5)
• EPA Substance Registry System: 4-(3-METHOXY-PHENYL)-3-OXO-BUTYRIC ACID ETHYL ESTER(324570-26-5)

Safety Data

• Hazardous Substances Data: 324570-26-5(Hazardous Substances Data)

Upstream product

• 64-17-5 ethanol 
• 879219-77-9 5-[1-hydroxy-2-(3-methoxy-phenyl)-ethylidene]-2,2-dimethyl-[1,3]dioxane-4,6-dione 
• 6834-42-0 3-methoxyphenylacetic acid chloride 
• 1798-09-0 m-methoxyphenylacetic acid 
• 2033-24-1 cycl-isopropylidene malonate 

Downstream Products

• 879219-78-0 6-(3-methoxy-benzyl)-1H-pyrimidine-2,4-dione 
• 879219-79-1 6-(3-hydroxy-benzyl)-1H-pyrimidine-2,4-dione 
• 1159576-81-4 ethyl (2Z)-3-amino-4-(3-methoxyphenyl)but-2-enoate 

Relevant articles and documents

COMPOUNDS AND USE THEREOF IN THE EXPANSION OF HEMATOPOIETIC STEM CELLS AND/OR HEMATOPOIETIC PROGENITOR CELLS

Compounds of general formula or salts or prodrugs thereof, are provided and described herein. The compounds are useful to expand hematopoietic stem cell and/or hematopoietic progenitor cell populations. Particularly, the hematopoietic cells are human cells. The compounds are also useful in the medical treatment of hematopoietic disorder/malignancy, an autoimmune disease and/or an inherited immune-deficient disease in a subject.

Acylation of Meldrum's acid with arylacetic acid imidazolides as a convenient method for the synthesis of 4-aryl-3-oxobutanoates

C-Acylation of Meldrum's acid by (het)arylacetic acids in ethanol in the presence of 1,1′-carbonyldiimidazole leads to ethyl 4-(het)aryl-3- oxobutanoates in high yields.

DNA-protein cross-linking: Model systems for pyrimidine-aromatic amino acid cross-linking

We have synthesized simple model systems to explore the possibility of photo-cross-linking between the pyrimidine bases and the side chains of the aromatic amino acids. Thymine/phenylalanine and thymine/tyrosine models gave cross-links, and thymine/tryptophan models gave complex mixtures; the cytosine/phenylalanine model was unreactive. The quantum yields for the model cross-linking reactions were 18-46 times smaller than those for thymine dimer formation. Biphotonic excitation contributes little to the yield of these reactions.

2-pyrazolin-5-ones

Chemical compounds having structural formula I and physiologically acceptable salts thereof, are inhibitors of serine/threonine and tyrosine kinase activity. Several of the tyrosine kinases, whose activity is inhibited by these chemical compounds, are involved in angiogenic processes. Thus, these chemical compounds can ameliorate disease states where angiogenesis or endothelial cell hyperproliferation is a factor. These compounds can be used to treat cancer and hyperproliferative disorders.