Welcome to LookChem.com Sign In|Join Free

CAS

  • or
Pyridine, 4-(2S)-oxiranyl- (9CI) is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

329281-08-5 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 329281-08-5 Structure
  • Basic information

    1. Product Name: Pyridine, 4-(2S)-oxiranyl- (9CI)
    2. Synonyms: Pyridine, 4-(2S)-oxiranyl- (9CI)
    3. CAS NO:329281-08-5
    4. Molecular Formula: C7H7NO
    5. Molecular Weight: 121.13658
    6. EINECS: N/A
    7. Product Categories: PYRIDINE
    8. Mol File: 329281-08-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Pyridine, 4-(2S)-oxiranyl- (9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: Pyridine, 4-(2S)-oxiranyl- (9CI)(329281-08-5)
    11. EPA Substance Registry System: Pyridine, 4-(2S)-oxiranyl- (9CI)(329281-08-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 329281-08-5(Hazardous Substances Data)

329281-08-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 329281-08-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,9,2,8 and 1 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 329281-08:
(8*3)+(7*2)+(6*9)+(5*2)+(4*8)+(3*1)+(2*0)+(1*8)=145
145 % 10 = 5
So 329281-08-5 is a valid CAS Registry Number.

329281-08-5Relevant articles and documents

Oxazolidinones as novel human CCR8 antagonists

Jin, Jian,Wang, Yonghui,Wang, Feng,Kerns, Jeffery K.,Vinader, Victoria M.,Hancock, Ashley P.,Lindon, Matthew J.,Stevenson, Graeme I.,Morrow, Dwight M.,Rao, Parvathi,Nguyen, Cuc,Barrett, Victoria J.,Browning, Chris,Hartmann, Guido,Andrew, David P.,Sarau, Henry M.,Foley, James J.,Jurewicz, Anthony J.,Fornwald, James A.,Harker, Andy J.,Moore, Michael L.,Rivero, Ralph A.,Belmonte, Kristen E.,Connor, Helen E.

, p. 1722 - 1725 (2007)

High-throughput screening of the corporate compound collection led to the discovery of a novel series of N-substituted-5-aryl-oxazolidinones as potent human CCR8 antagonists. The synthesis, structure-activity relationships, and optimization of the series

Nucleophilic Organic Base DABCO-Mediated Chemospecific Meinwald Rearrangement of Terminal Epoxides into Methyl Ketones

Li, Siqi,Shi, Yi,Li, Pingfan,Xu, Jiaxi

, p. 4443 - 4450 (2019/04/30)

Nucleophilic organic base DABCO (1,4-diazabicyclo[2.2.2]octane)-mediated Meinwald rearrangement of various epoxides was investigated. 2-Aryl-, alkenyl-, and alkynylepoxides generate the corresponding methyl ketones chemospecifically in good to excellent yields. The current DABCO-mediated Meinwald rearrangement of epoxides features readily accessible starting materials, a wide substrate scope, a transition-metal- and acid-free environment, and chemospecificity in the isomerization of epoxides.

Manganese(II)/Picolinic Acid Catalyst System for Epoxidation of Olefins

Moretti, Ross A.,Du Bois,Stack, T. Daniel P.

supporting information, p. 2528 - 2531 (2016/07/06)

An in situ generated catalyst system based on Mn(CF3SO3)2, picolinic acid, and peracetic acid converts an extensive scope of olefins to their epoxides at 0 °C in 5 min, with remarkable oxidant efficiency and no evidence of radical behavior. Competition experiments indicate an electrophilic active oxidant, proposed to be a high-valent Mn = O species. Ligand exploration suggests a general ligand sphere motif contributes to effective oxidation. The method is underscored by its simplicity and use of inexpensive reagents to quickly access high value-added products.

Stereoselective epoxidation of alkenes with hydrogen peroxide using a bipyrrolidine-based family of manganese complexes

Garcia-Bosch, Isaac,Gomez, Laura,Polo, Alfonso,Ribas, Xavi,Costas, Miquel

supporting information; experimental part, p. 65 - 70 (2012/03/27)

Novel manganese complexes containing N4-tetradentate ligands derived from chiral bipyrrolidinediamines catalyze the stereoselective epoxidation of a wide array of alkenes using low catalyst loadings (0.1 mol%) and hydrogen peroxide (1.2 equiv.) as terminal oxidant. This family of catalysts affords good to excellent yields (80-100%) and moderate to good ees (40-73%) in short reaction times (30 min) making efficient use of hydrogen peroxide.

Efficient biocatalysis for the production of enantiopure (S)-epoxides using a styrene monooxygenase (SMO) and Leifsonia alcohol dehydrogenase (LSADH) system

Toda, Hiroshi,Imae, Ryouta,Itoh, Nobuya

, p. 1542 - 1549 (2013/02/21)

Herein we report the production of enantiopure epoxides through biocatalysis using recombinant Escherichia coli cells expressing Rhodococcus sp. ST-10 styrene monooxygenase (SMO) and Leifsonia sp. S749 alcohol dehydrogenase (LSADH) genes are described. Rhodococcus sp. ST-10 SMO catalyzed the epoxidation of various alkenes, including styrene derivatives, vinyl pyridines, and linear alkenes, to give (S)-epoxides. NADH was regenerated by the reduction of NAD + by LSADH with 2-propanol. The E. coli biocatalyst was used in an aqueous/organic biphasic reaction system and the reaction conditions were optimized. Under the optimized conditions, 170 mM of (S)-styrene oxide was obtained from styrene in the organic phase with excellent enantiomeric excess (99.8%). This biocatalytic process was used to synthesize various (S)-epoxides.

Novel Ethanediamone Hepcidine Antagonists

-

, (2012/09/05)

The present invention relates to novel hepcidin antagonists of formula (I), pharmaceutical compositions comprising them and the use thereof as medicaments, in particular for treatment of disorders in iron metabolism, such as, in particular, iron deficiency diseases and anaemias, in particular anaemias in connection with chronic inflammatory diseases (ACD: anaemia of chronic disease and AI: anaemia of inflammation).

HETEROCYCLIC COMPOUNDS

-

Page/Page column 19, (2008/06/13)

The invention is related to novel substituted diazaheterocycles useful as effective antihypercholesterolemic agents, methods of their preparation, and pharmaceutical compositions containing them.

INHIBITORS OF AKT ACTIVITY

-

Page/Page column 125, (2008/06/13)

Invented are novel 1 H-imidazo[4,5-c]pyridin-2-yl compounds, the use of such compounds as inhibitors of protein kinase B activity and in the treatment of cancer and arthritis.

NOVEL DERIVATIVES OF PYRIDYLETHANOL (PHENYLETHYL) AMINES AS INHIBITORS OF CHOLESTEROL BIOSYNTHESIS, PROCESSES FOR THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

-

Page 20, (2008/06/13)

The novel derivatives of pyridylethanol (phenylethyl) amines of formula I are described wherein n is an integer from 1 to 4, R1 is a hydrogen atom, hydroxyl group or lower C1-6 alkoxy group R2 is a hydrogen atom or a straight or branched lower C1-6 alkyl group X, is hydrogen, fluorine, chlorine, bromine, hydroxyl group, trifluoromethyl group, 3,4-di-CI,2,4-di-CI or lower C1-6 alkoxy group, the enantiomers, diastereoisomers or racemates thereof or the physiologically acceptable acid addition salts thereof which are ligands of sigma receptors for inhibiting cholesterol biosynthesis and are thus appropriate for the treatment of hypercholesterolemia and hyperlipemia in humans. The greatest lowering of cholesterol was observed by 1-(d-pyridyl)-2-(N-(2-(3,4-dicholorophenyl)ethyl-N-propylamino)ethanol in the form of dihydrobromide salt (signature BK-35. 2HBr).

Microbiological transformations. 47. A step toward a green chemistry preparation of enantiopure (S)-2-, -3-, and -4-pyridyloxirane via an epoxide hydrolase catalyzed kinetic resolution

Genzel,Archelas,Broxterman,Schulze,Furstoss

, p. 538 - 543 (2007/10/03)

The biocatalyzed hydrolytic kinetic resolution of 2-, 3-, and 4-pyridyloxirane by the Aspergillus niger epoxide hydrolase (EH) has been explored. This was used to perform a gram scale preparation of these epoxides of (S) absolute configuration using a process performed at a concentration as high as 10 g/L (82 mM). All three epoxides have been obtained in a nearly enantiopure form (ee > 98%). Interestingly, it was shown that this biotransformation could be achieved using plain water instead of buffer solution, an important improvement as far as downstream processing of an eventual industrial process is concerned. Neither of these substrates could be obtained in reasonable enantiomeric purity and yield using the nowadays most efficient metal-based catalysts.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 329281-08-5