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CAS

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32970-32-4

5-Acetyl-6-amino-1,3-dimethyluracil is a heterocyclic chemical compound with the molecular formula C8H10N4O2. It is a derivative of uracil and is known for its potential applications in the pharmaceutical and chemical industries due to its antiviral and antitumor activities.

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  • 32970-32-4 Structure

  • Basic information

    1. Product Name: 5-Acetyl-6-amino-1,3-dimethyluracil
    2. Synonyms: 5-Acetyl-6-amino-1,3-dimethyluracil;5-Acetyl-6-amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione;5-Acetyl-6-amino-1,3-dimethyl-2,4(1H,3H)-pyrimidinedione;5-acetyl-6-amino-1,3-dimethyl-pyrimidine-2,4-dione;5-acetyl-6-amino-1,3-dimethylpyrimidine-2,4-dione;5-acetyl-6-amino-1,3-dimethyl-pyrimidine-2,4-quinone;6-amino-5-ethanoyl-1,3-dimethyl-pyrimidine-2,4-dione;MLS000089916
    3. CAS NO:32970-32-4
    4. Molecular Formula: C8H11N3O3
    5. Molecular Weight: 197.19124
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 32970-32-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 308.9°Cat760mmHg
    3. Flash Point: 140.6°C
    4. Appearance: /
    5. Density: 1.317g/cm3
    6. Vapor Pressure: 0.00066mmHg at 25°C
    7. Refractive Index: 1.549
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 5-Acetyl-6-amino-1,3-dimethyluracil(CAS DataBase Reference)
    11. NIST Chemistry Reference: 5-Acetyl-6-amino-1,3-dimethyluracil(32970-32-4)
    12. EPA Substance Registry System: 5-Acetyl-6-amino-1,3-dimethyluracil(32970-32-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 32970-32-4(Hazardous Substances Data)

32970-32-4 Usage

Uses

Used in Pharmaceutical Industry:
5-Acetyl-6-amino-1,3-dimethyluracil is used as a building block for the synthesis of pharmaceuticals, leveraging its antiviral and antitumor properties. It serves as a key component in the development of new drugs targeting various viral and cancerous conditions.
Used in Agrochemical Industry:
In the agrochemical sector, 5-Acetyl-6-amino-1,3-dimethyluracil is utilized as a precursor in the synthesis of agrochemicals, contributing to the development of products that can protect crops from viral infections and other diseases.
Used in Chemical Reactions and Modifications:
Due to its structure and properties, 5-Acetyl-6-amino-1,3-dimethyluracil is employed in various chemical reactions and modifications, allowing for the creation of a wide range of compounds with diverse applications in both the pharmaceutical and chemical industries.

Check Digit Verification of cas no

The CAS Registry Mumber 32970-32-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,2,9,7 and 0 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 32970-32:
(7*3)+(6*2)+(5*9)+(4*7)+(3*0)+(2*3)+(1*2)=114
114 % 10 = 4
So 32970-32-4 is a valid CAS Registry Number.
InChI:InChI=1/C8H11N3O3/c1-4(12)5-6(9)10(2)8(14)11(3)7(5)13/h9H2,1-3H3

32970-32-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-acetyl-6-amino-1,3-dimethylpyrimidine-2,4-dione

1.2 Other means of identification

Product number -
Other names 5-acetyl-6-amino-1,3-dimethyl-1H-pyrimidine-2,4-dione

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:32970-32-4 SDS

32970-32-4Relevant articles and documents

Selective Inhibitors of a Human Prolyl Hydroxylase (OGFOD1) Involved in Ribosomal Decoding

Thinnes, Cyrille C.,Lohans, Christopher T.,Abboud, Martine I.,Yeh, Tzu-Lan,Tumber, Anthony,Nowak, Rados?aw P.,Attwood, Martin,Cockman, Matthew E.,Oppermann, Udo,Loenarz, Christoph,Schofield, Christopher J.

supporting information, p. 2019 - 2024 (2019/01/11)

Human prolyl hydroxylases are involved in the modification of transcription factors, procollagen, and ribosomal proteins, and are current medicinal chemistry targets. To date, there are few reports on inhibitors selective for the different types of prolyl hydroxylases. We report a structurally informed template-based strategy for the development of inhibitors selective for the human ribosomal prolyl hydroxylase OGFOD1. These inhibitors did not target the other human oxygenases tested, including the structurally similar hypoxia-inducible transcription factor prolyl hydroxylase, PHD2.

Synthesis and pharmacology of pyrido[2,3-d]pyrimidinediones bearing polar substituents as adenosine receptor antagonists

Bulicz, Jacek,Bertarelli, Daniela C.G.,Baumert, Dieter,Fuelle, Friederike,Mueller, Christa E.,Heber, Dieter

, p. 2837 - 2849 (2007/10/03)

Amino-substituted pyrido[2,3-d]pyrimidinediones have previously been found to bind to adenosine A1 and A2A receptors in micromolar concentrations. The present study was aimed at studying the structure-activity relationships of this c

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