329934-78-3Relevant articles and documents
Synthesis and structure-activity relationship of tetrahydropyrazolopyrimidine derivatives - A novel structural class of potent calcium-sensing receptor antagonists
Yoshida, Masato,Mori, Akira,Inaba, Atsuhiro,Oka, Masahiro,Makino, Haruhiko,Yamaguchi, Masashi,Fujita, Hisashi,Kawamoto, Tomohiro,Goto, Mika,Kimura, Hiroyuki,Baba, Atsuo,Yasuma, Tsuneo
experimental part, p. 8501 - 8511 (2011/02/23)
A series of novel tetrahydropyrazolopyrimidine derivatives containing an adamantyl group were synthesized and evaluated as potential calcium-sensing receptor (CaSR) antagonists. After chemical modification of 9a, which was identified as a hit compound in