331833-99-9 Usage
Uses
Used in Medicinal Chemistry:
5-Bromobenzofuran-2-ylboronic acid is used as a building block for the synthesis of biologically active molecules, contributing to the development of new pharmaceuticals. Its unique structure and reactivity in cross-coupling reactions facilitate the creation of diverse and complex organic compounds with potential therapeutic applications.
Used in Drug Discovery and Development:
In the field of drug discovery and development, 5-bromobenzofuran-2-ylboronic acid is utilized as a key intermediate in the synthesis of novel compounds with potential medicinal properties. Its ability to form carbon-carbon bonds through Suzuki-Miyaura cross-coupling reactions is crucial for constructing molecular frameworks that can exhibit specific biological activities.
Used in Chemical Biology Studies:
5-Bromobenzofuran-2-ylboronic acid is used as a fluorescent reagent in chemical biology, where its optical properties allow for the tracking and visualization of molecular interactions and processes within biological systems. This application aids researchers in understanding complex biological phenomena and can contribute to the advancement of diagnostic and therapeutic strategies.
Used in Organic Synthesis:
As a versatile reagent in organic synthesis, 5-bromobenzofuran-2-ylboronic acid is employed for the formation of carbon-carbon bonds through Suzuki-Miyaura cross-coupling reactions. This capability is essential for the construction of a wide range of organic compounds, including those with potential applications in various industries such as pharmaceuticals, agrochemicals, and materials science.
Used in the Synthesis of Biologically Active Molecules:
5-Bromobenzofuran-2-ylboronic acid is used as a precursor in the synthesis of biologically active molecules, which are crucial for probing biological targets and developing new therapeutic agents. Its unique structural features and reactivity make it a valuable component in the design and synthesis of molecules with specific biological activities and potential applications in medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 331833-99-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,1,8,3 and 3 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 331833-99:
(8*3)+(7*3)+(6*1)+(5*8)+(4*3)+(3*3)+(2*9)+(1*9)=139
139 % 10 = 9
So 331833-99-9 is a valid CAS Registry Number.
331833-99-9Relevant articles and documents
INHIBITORS OF HEPATITIS C VIRUS REPLICATION
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Paragraph 0953, (2019/05/15)
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
INHIBITORS OF HEPATITIS C VIRUS REPLICATION
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Page/Page column 158, (2010/11/04)
The present invention relates to compounds of formula (I) that are useful as hepatitis C virus (HCV) NS5A inhibitors, the synthesis of such compounds, and the use of such compounds for inhibiting HCV NS5A activity, for treating or preventing HCV infections and for inhibiting HCV viral replication and/or viral production in a cell-based system.
The synthesis and transition temperatures of 2-(4-alkyl- and 4-alkoxy-phenyl)-5-cyano-1-benzofurans and related diaryl-1-benzofurans - An assessment of how deviations from linearity and conformational effects in a core unit affect mesogenicity
Friedman,Toyne,Goodby,Hird
, p. 2759 - 2772 (2007/10/03)
The synthesis and transition temperatures are reported for several 2-(4-alkyl- and 4-alkoxy-phenyl)-5-cyano-1-benzofurans, 2-(4′-alkylbiphenyl-4-yl)-5-cyano- and 5-(4′-alkylbiphenyl-4-yl)-2-cyano-1-benzofurans, and for compounds with other combinations of terminal alkyl and cyano groups in 2,5-disubstituted-1-benzofurans containing two phenyl units, some isolated examples of related cyclohexane systems are also presented. The mesogenic behaviour of these compounds and several intermediates (e.g. amides, acids and esters) is discussed and the transition temperatures are rationalised on the following basis (a) 1-benzofuran is a superior core unit to benzene, (b) 2,5-disubstitution in 1-benzofuran gives a bent core which adversely affects mesogenicity, to an extent which depends on its position in the core, (c) antiparallel associations in terminal cyano compounds can eliminate the disadvantage of a bent core structure, (d) 2-aryl-1-benzofurans have negligible inter-annular twist but 5-aryl-1-benzofurans have similar inter-annular twist to that in biphenyls.
