129969-69-3

Basic information

• Product Name: 4-(2,2-Dimethoxyethoxy)bromobenzene
• Synonyms: 4-(2,2-Dimethoxyethoxy)bromobenzene;1-bromo-4-(2,2-dimethoxyethoxy)Benzene
• CAS NO: 129969-69-3
• Molecular Formula: C₁₀H₁₃BrO₃
• Molecular Weight: 261
• Mol File: 129969-69-3.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(2,2-Dimethoxyethoxy)bromobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2,2-Dimethoxyethoxy)bromobenzene(129969-69-3)
• EPA Substance Registry System: 4-(2,2-Dimethoxyethoxy)bromobenzene(129969-69-3)

Safety Data

• Hazardous Substances Data: 129969-69-3(Hazardous Substances Data)

Usage

General Description

4-(2,2-Dimethoxyethoxy)bromobenzene is a chemical compound with the molecular formula C10H13BrO3. It is a brominated aromatic compound with four methoxy groups and one bromine atom attached to a benzene ring. 4-(2,2-Dimethoxyethoxy)bromobenzene is commonly used as a precursor in organic synthesis for the preparation of various organic compounds. It is also used as a building block in the production of pharmaceuticals, agrochemicals, and other fine chemicals. The presence of the bromine atom and the methoxy groups provides unique reactivity and properties to this compound, making it useful in a wide range of chemical reactions and applications. Additionally, it is important to handle this compound with care, as it may pose certain hazards to human health and the environment.

Upstream product

• 7252-83-7 1-bromo-2,2-dimethoxyethane 
• 106-41-2 4-bromo-phenol 
• 97-97-2 chloroacetaldehyde dimethyl acetal 

Downstream Products

• 1093281-33-4 4-(benzofuran-5-yl)benzaldehyde 
• 331834-04-9 C₁₉H₂₁BO₃ 
• 331834-00-5 5-bromo-2-(4-pentyl-phenyl)-benzofuran 
• 331834-03-8 5-(4-pentyl-phenyl)-benzofuran 
• 331833-99-9 (5-bromobenzofuran-2-yl)boronic acid 
• 79002-39-4 benzo[b]furan-5-carbonitrile 
• 23145-07-5 5-bromobenzofuran 

Relevant articles and documents

Rhodium-Catalyzed Intermolecular Cyclopropanation of Benzofurans, Indoles, and Alkenes via Cyclopropene Ring Opening

The generation of metal carbenoids via ring opening of cyclopropenes by transition metals offers a simple entry into highly reactive intermediates. Herein, we describe a diastereoselective intermolecular rhodium-catalyzed cyclopropanation of heterocycles and alkenes using cyclopropenes as carbene precursors with a low loading of a commercially available rhodium catalyst. The reported method is scalable and could be performed with catalyst loadings as low as 0.2 mol %, with no impact to the reaction yield or selectivity.

5-bromo-benzofuran preparation method

The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of 5-bromobenzofuran. The preparation method of 5-bromobenzofuran comprises the following steps: p-bromophenol and 2-bromoacetaldehyde dimethyl aceta

The synthesis and transition temperatures of 2-(4-alkyl- and 4-alkoxy-phenyl)-5-cyano-1-benzofurans and related diaryl-1-benzofurans - An assessment of how deviations from linearity and conformational effects in a core unit affect mesogenicity

The synthesis and transition temperatures are reported for several 2-(4-alkyl- and 4-alkoxy-phenyl)-5-cyano-1-benzofurans, 2-(4′-alkylbiphenyl-4-yl)-5-cyano- and 5-(4′-alkylbiphenyl-4-yl)-2-cyano-1-benzofurans, and for compounds with other combinations of terminal alkyl and cyano groups in 2,5-disubstituted-1-benzofurans containing two phenyl units, some isolated examples of related cyclohexane systems are also presented. The mesogenic behaviour of these compounds and several intermediates (e.g. amides, acids and esters) is discussed and the transition temperatures are rationalised on the following basis (a) 1-benzofuran is a superior core unit to benzene, (b) 2,5-disubstitution in 1-benzofuran gives a bent core which adversely affects mesogenicity, to an extent which depends on its position in the core, (c) antiparallel associations in terminal cyano compounds can eliminate the disadvantage of a bent core structure, (d) 2-aryl-1-benzofurans have negligible inter-annular twist but 5-aryl-1-benzofurans have similar inter-annular twist to that in biphenyls.