129969-69-3Relevant articles and documents
Rhodium-Catalyzed Intermolecular Cyclopropanation of Benzofurans, Indoles, and Alkenes via Cyclopropene Ring Opening
Jeyaseelan, Rubaishan,Lautens, Mark,Ross, Rachel J.
supporting information, (2020/06/29)
The generation of metal carbenoids via ring opening of cyclopropenes by transition metals offers a simple entry into highly reactive intermediates. Herein, we describe a diastereoselective intermolecular rhodium-catalyzed cyclopropanation of heterocycles and alkenes using cyclopropenes as carbene precursors with a low loading of a commercially available rhodium catalyst. The reported method is scalable and could be performed with catalyst loadings as low as 0.2 mol %, with no impact to the reaction yield or selectivity.
REACTIVE MESOGEN, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY COMPRISING THE SAME
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Paragraph 0108; 0109; 0110; 0111; 0112, (2019/01/24)
The invention relates to a reactive mesogen, a liquid crystal composition and a liquid crystal display comprising the same. The reactive mesogen is represented by a chemical formula 1, wherein, X1 andX2 independently are hydrogen or halogen, Y is -O-, -S-
5-bromo-benzofuran preparation method
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Paragraph 0026, (2017/04/06)
The invention belongs to the field of organic synthesis, and particularly relates to a preparation method of 5-bromobenzofuran. The preparation method of 5-bromobenzofuran comprises the following steps: p-bromophenol and 2-bromoacetaldehyde dimethyl aceta
AZABENZIMIDAZOLES AS FATTY ACID SYNTHASE INHIBITORS
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Page/Page column 52, (2011/06/23)
This invention relates to the use of azabenzimidazole derivatives for the modulation, notably the inhibition of the activity or function of fatty acid synthase (FAS). Suitably, the present invention relates to the use of azabenzimidazoles in the treatment of cancer.
The synthesis and transition temperatures of 2-(4-alkyl- and 4-alkoxy-phenyl)-5-cyano-1-benzofurans and related diaryl-1-benzofurans - An assessment of how deviations from linearity and conformational effects in a core unit affect mesogenicity
Friedman,Toyne,Goodby,Hird
, p. 2759 - 2772 (2007/10/03)
The synthesis and transition temperatures are reported for several 2-(4-alkyl- and 4-alkoxy-phenyl)-5-cyano-1-benzofurans, 2-(4′-alkylbiphenyl-4-yl)-5-cyano- and 5-(4′-alkylbiphenyl-4-yl)-2-cyano-1-benzofurans, and for compounds with other combinations of terminal alkyl and cyano groups in 2,5-disubstituted-1-benzofurans containing two phenyl units, some isolated examples of related cyclohexane systems are also presented. The mesogenic behaviour of these compounds and several intermediates (e.g. amides, acids and esters) is discussed and the transition temperatures are rationalised on the following basis (a) 1-benzofuran is a superior core unit to benzene, (b) 2,5-disubstitution in 1-benzofuran gives a bent core which adversely affects mesogenicity, to an extent which depends on its position in the core, (c) antiparallel associations in terminal cyano compounds can eliminate the disadvantage of a bent core structure, (d) 2-aryl-1-benzofurans have negligible inter-annular twist but 5-aryl-1-benzofurans have similar inter-annular twist to that in biphenyls.