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4-BroMo-3-nitro-benzoyl chloride is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 335015-51-5 Structure
  • Basic information

    1. Product Name: 4-BroMo-3-nitro-benzoyl chloride
    2. Synonyms: 4-BroMo-3-nitro-benzoyl chloride
    3. CAS NO:335015-51-5
    4. Molecular Formula: C7H3BrClNO3
    5. Molecular Weight: 264
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 335015-51-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 4-BroMo-3-nitro-benzoyl chloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: 4-BroMo-3-nitro-benzoyl chloride(335015-51-5)
    11. EPA Substance Registry System: 4-BroMo-3-nitro-benzoyl chloride(335015-51-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 335015-51-5(Hazardous Substances Data)

335015-51-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 335015-51-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,5,0,1 and 5 respectively; the second part has 2 digits, 5 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 335015-51:
(8*3)+(7*3)+(6*5)+(5*0)+(4*1)+(3*5)+(2*5)+(1*1)=105
105 % 10 = 5
So 335015-51-5 is a valid CAS Registry Number.

335015-51-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-bromo-3-nitrobenzoyl chloride

1.2 Other means of identification

Product number -
Other names 4-Brom-3-nitro-benzoylchlorid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:335015-51-5 SDS

335015-51-5Relevant articles and documents

Discovery of novel β-carboline derivatives as selective AChE inhibitors with GSK-3β inhibitory property for the treatment of Alzheimer's disease

Liu, Wenwu,Liu, Xin,Liu, Wenjie,Gao, Yaping,Wu, Limeng,Huang, Yaoguang,Chen, Huanhua,Li, Deping,Zhou, Lijun,Wang, Nan,Xu, Zihua,Jiang, Xiaowen,Zhao, Qingchun

, (2022/01/12)

The natural product harmine, a representative β-carboline alkaloid from the seeds of Peganum harmala L. (Zygophyllaceae), possesses a broad spectrum of biological activities. In this study, a novel series of harmine derivatives containing N-benzylpiperidi

Design, synthesis and biological evaluation of harmine derivatives as potent GSK-3β/DYRK1A dual inhibitors for the treatment of Alzheimer's disease

Liu, Wenwu,Liu, Xin,Tian, Liting,Gao, Yaping,Liu, Wenjie,Chen, Huanhua,Jiang, Xiaowen,Xu, Zihua,Ding, Huaiwei,Zhao, Qingchun

, (2021/06/21)

Alzheimer's disease (AD) is a chronic and progressive neurodegenerative disease, characterized by irreversible cognitive impairment, memory loss and behavioral disturbances, ultimately leading to death. Glycogen synthase kinase 3β (GSK-3β) and dual-specificity tyrosine phosphorylation regulated kinase1A (DYRK1A) have gained a lot of attention for its role in tau pathology. To search for potential dual GSK-3β/DYRK1A inhibitors, we focused on harmine, a natural β-carboline alkaloid, which has been extensively studied for its various biological effects on the prevention of AD. In this study, a new series of harmine derivatives were designed, synthesized and evaluated as dual GSK-3β/DYRK1A inhibitors for their multiple biological activities. The in vitro results indicated that most of them displayed promising activity against GSK-3β and DYRK1A. Among them, compound ZDWX-25 showed potent inhibitory effects on GSK-3β and DYRK1A with IC50 values of 71 and 103 nM, respectively. Molecular modelling and kinetic studies verified that ZDWX-25 could interact with the ATP binding pocket of GSK-3β and DYRK1A. Western blot analysis revealed that ZDWX-25 inhibited hyperphosphorylation of tau protein in okadaic acid (OKA)-induced SH-SY5Y cells. In addition, ZDWX-25 showed good blood-brain barrier penetrability in vitro. More importantly, ZDWX-25 could ameliorate the impaired learning and memory in APP/PS1/Tau transgenic mice. These results indicated that the harmine-based compounds could be served as promising dual-targeted candidates for AD.

Beta-carboboline GSK3beta/DYRK1A dual inhibitor and preparation method thereof and application of beta-carboboline GSK3beta/DYRK1A dual inhibitor in resisting Alzheimer's disease

-

Paragraph 0195-0198, (2021/07/08)

The invention discloses a beta-carboline GSK3beta/DYRK1A dual inhibitor as shown in a general formula I, a preparation method of the beta-carboline GSK3beta/DYRK1A dual inhibitor and application of the beta-carboline GSK3beta/DYRK1A dual inhibitor in resi

NOVEL CLASS OF QUINOLONE HETEROCYCLIC AROMATIC MOLECULES FOR CANCER TREATMENT

-

Paragraph 0099, (2018/05/24)

The invention is directed to new class of quinolone heterocyclic aromatic molecules (Renotinibs) and their use in the treatment of cancer, in particular, cancer that harbor abnormal human epidermal growth factor receptors (EGFRs).

Elongated and substituted triazine-based tricarboxylic acid linkers for MOFs

Klinkebiel, Arne,Beyer, Ole,Malawko, Barbara,Lüning, Ulrich

supporting information, p. 2267 - 2273 (2016/11/17)

New triazine-based tricarboxylic acid linkers were prepared as elongated relatives of triazinetribenzoic acid (TATB). Additionally, functional groups (NO2, NH2, OMe, OH) were introduced for potential post-synthetic modification (PSM) of MOFs. Functionalized tris(4-bromoaryl)triazine "cores" (3a,3b) were obtained by unsymmetric trimerization mixing one equivalent of an acid chloride (OMe or NO2 substituted) with two equivalents of an unsubstituted nitrile. Triple Suzuki coupling of the cores 3 with suitable phenyl- and biphenylboronic acid derivatives provided elongated tricarboxylic acid linkers as carboxylic acids 17 and 20 or their esters 16 and 19. Reduction of the nitro group and cleavage of the methoxy group gave the respective amino and hydroxy-substituted triazine linkers.

FACTOR XIa INHIBITORS

-

Page/Page column 51, (2016/11/02)

The present invention provides a compound of Formula (I); and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing thromboses, embolisms, hypercoagulability or fibrotic changes. The compounds are selective Factor XIa inhibitors or dual inhibitors of Factor XIa and plasma kallikrein.

The flocculated acryloyldimethyltauric molecule ligand

-

Paragraph 0589, (2016/10/08)

Provided are certain benzothiazole, imidazothiazole, imidazopyrimidine and imidazopyridine compounds, including, for example: formula (I) and pharmaceutically and physiologically acceptable salts, hydrates, and solvates thereof. Such compounds can be used as diagnostic ligands or labels of tau protein and PHF.

BIPHENYL CARBOXYLIC AMIDE P38 KINASE INHIBITORS

-

Page 54, (2008/06/13)

Compounds of formula (I) or pharmaceutically acceptable derivatives thereof, and their use as pharmaceuticals, particularly as p38 kinase inhibitors.

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