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CAS

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335166-36-4

iMAC2 is a chemical compound that serves as a potent and selective inhibitor of the enzyme macrophage migration inhibitory factor (MIF). It is characterized by its ability to bind to the active site of MIF, thereby disrupting its function. iMAC2's high specificity and unique mechanism of action make it a valuable tool in research and experimental studies, particularly for investigating the role of MIF in disease pathogenesis and for developing targeted therapies.

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  • 335166-36-4 Structure

  • Basic information

    1. Product Name: iMAC2
    2. Synonyms: iMAC2
    3. CAS NO:335166-36-4
    4. Molecular Formula: C19H20Br2FN3
    5. Molecular Weight: 469.1886032
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 335166-36-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: iMAC2(CAS DataBase Reference)
    10. NIST Chemistry Reference: iMAC2(335166-36-4)
    11. EPA Substance Registry System: iMAC2(335166-36-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 335166-36-4(Hazardous Substances Data)

335166-36-4 Usage

Uses

Used in Pharmaceutical Research:
iMAC2 is used as a research tool for studying the role of MIF in various diseases, including inflammatory diseases, cancer, and other immune-related conditions. Its high specificity and potency in inhibiting MIF make it an essential compound for understanding the enzyme's function and its implications in disease processes.
Used in Drug Development:
iMAC2 is used as a lead compound in the development of targeted therapies for inflammatory diseases, cancer, and other immune-related conditions. By inhibiting the activity of MIF, iMAC2 has the potential to treat these conditions more effectively and with fewer side effects compared to traditional treatments.
Used in Experimental Studies:
iMAC2 is used as an experimental agent in various in vitro and in vivo studies to evaluate its efficacy and safety in treating diseases associated with MIF. These studies help to determine the optimal dosage, administration route, and potential side effects of iMAC2, providing valuable information for its further development and clinical application.
Used in Diagnostic Applications:
iMAC2 can be used as a diagnostic tool to assess the activity of MIF in patients with inflammatory diseases, cancer, and other immune-related conditions. By measuring the levels of MIF inhibition by iMAC2, clinicians can monitor the progression of the disease and the effectiveness of the treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 335166-36-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,3,5,1,6 and 6 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 335166-36:
(8*3)+(7*3)+(6*5)+(5*1)+(4*6)+(3*6)+(2*3)+(1*6)=134
134 % 10 = 4
So 335166-36-4 is a valid CAS Registry Number.

335166-36-4Downstream Products

335166-36-4Relevant articles and documents

3,6-Dibromocarbazole piperazine derivatives of 2-propanol as first inhibitors of cytochrome C release via bax channel modulation

Bombrun, Agnes,Gerber, Patrick,Casi, Giulio,Terradillos, Olivier,Antonsson, Bruno,Halazy, Serge

, p. 4365 - 4368 (2007/10/03)

There is compelling evidence that Bax channel activity stimulates cytochrome c release leading ultimate]y to cell death, which is a key event in ischemic injuries and neurodegenerative diseases. Here 3,6-dibromocarbazole piperazine derivatives of 2-propan

9-(Piperazinylalkyl)carbazoles as Bax-modulators

-

, (2008/06/13)

The present invention is related to piperazine derivatives of carbazole notably for use as pharmaceutically active compounds, as well as to pharmaceutical formulations containing such piperazine derivatives of carbazole. Said piperazine derivatives of car

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