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3-[(2-Hydroxyethyl)amino]propiononitrile is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

33759-44-3

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33759-44-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 33759-44-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,7,5 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 33759-44:
(7*3)+(6*3)+(5*7)+(4*5)+(3*9)+(2*4)+(1*4)=133
133 % 10 = 3
So 33759-44-3 is a valid CAS Registry Number.
InChI:InChI=1/C5H10N2O/c6-2-1-3-7-4-5-8/h7-8H,1,3-5H2

33759-44-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(2-hydroxyethylamino)propanenitrile

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:33759-44-3 SDS

33759-44-3Relevant articles and documents

Green synthesis of CuO nanoparticles using: Lantana camara flower extract and their potential catalytic activity towards the aza-Michael reaction

Chowdhury, Rakesh,Khan, Aslam,Rashid, Md. Harunar

, p. 14374 - 14385 (2020/04/23)

Aza-Michael addition is one of the most exploited reactions in organic chemistry. It is regarded as one of the most popular and efficient methods for the creation of the carbon-nitrogen bond, which is a key feature of many bioactive molecules. Herein, we report the synthesis of CuO nanoparticles by an alkaline hydrolysis process in the presence of the flower extract of Lantana camara, an invasive weed, followed by calcination in air at 400 °C. Microscopic results indicated that the plant extract played an important role in the modulation of the size and shape of the product. In the presence of extract, porous CuO nanostructures are formed. While mostly aggregated rod-shaped CuO nanostructures are formed in the absence of extract. The products are pure and highly crystalline possessing the monoclinic phase. The CuO nanoparticles have been used as a catalyst in the aza-Michael addition reaction in aqueous medium under ultrasound vibration. The product yield is excellent and the catalyst is reusable up to the fifth cycle. The catalyst system can be extended to various substituted substrates with excellent to moderate yields.

Synthesis and Catalytic Application of Mixed Valence Iron (FeII/FeIII)-Based OMS-MIL-100(Fe) as an Efficient Green Catalyst for the aza-Michael Reaction

Rostamnia, Sadegh,Alamgholiloo, Hassan

, p. 2918 - 2928 (2018/07/30)

Abstract: In the present study, open metal site iron-based MOF [MIL-100(Fe)], by a solvothermal method with polygonal morphology, are synthesised and then applied as a heterogeneous green catalyst for aza-Michael addition of various amines with α, β-unsaturated compounds. The MIL-100(Fe) was found to be efficient, selective, green and heterogeneous catalyst for the aza-Michael reaction. The proposed catalyst has better recyclability and can be reused six times without apparent loss of activity. Graphical Abstract: [Figure not available: see fulltext.].

A structure-based design approach to advance the allyltyrosine-based series of HIV integrase inhibitors

Gordon, Christopher P.,Dalton, Neal,Vandegraaff, Nicholas,Deadman, John,Rhodes, David I.,Coates, Jonathan A.,Pyne, Stephen G.,Griffith, Renate,Bremner, John B.,Keller, Paul A.

, p. 1253 - 1268 (2017/12/04)

As of mid-2017, only one structure of the human immunodeficiency virus (HIV) integrase core domain co-crystallised with an active site inhibitor was reported. In this structure (1QS4), integrase is complexed with a diketo-acid based strand-transfer inhibitor (INSTI). This structure has been a preferred platform for the structure-based design of INSTIs despite concerns relating to structural irregularities arising from crystallographic packing effects. A survey of the current pool of 297 reported integrase catalytic core structures indicated that the anatomy of the active site in the complex structure 1QS4 exhibits subtle variations relative to all other structures examined. Consequently, the 1QS4 structure was employed for docking studies. From the docking of twenty-seven allyltyrosine analogues, a 3-point inhibitor binding motif required for activity was established and successfully utilised in the development of a tripeptide displaying an EC50 value of 10 ± 5 μM in HIV infected human T-cells. Additional docking of “in-house” compound libraries unearthed a methyl ester based nitrile derivative displaying an IC50 value of 0.5 μM in a combined 3′-processing and strand-transfer assay.

Iodine-alumina catalyzed Aza- michael addition under solvent free conditions

Saikia, Monmi,Kakati, Dwipen,Joseph, Maria Stalin,Sarma, Jadab Chandra

experimental part, p. 654 - 658 (2010/06/15)

An efficient aza-Michael addition of amines to a variety of activated olefins was carried out under solvent free conditions using iodine-alumina as a catalyst at room temperature or under microwave irradiation (in case of solid) in high yield. 2009 Bentham Science Publishers Ltd.

BENZOXAZOLE ACETONITRILES

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Page/Page column 38, (2010/02/11)

The present invention is related to benzoxazole acetonitriles as well as to pharmaceutical formulations containing such benzoxazole acetonitriles pof formula (I). Said benzoxazole acetonitriles are useful in the treatment of metabolic disorders mediated b

SYNTHESIS OF 3-(2-CYANOETHYL)OXAZOLIDINES AND THEIR USE FOR CONCENTRATING LEAD-ZINC SULFIDE ORES

Kukharev, B. F.,Stankevich, V. K.,Klimenko, G. R.,Kiseleva, M. A.,Leonov, S. B.

, p. 1813 - 1814 (2007/10/03)

A series of 3-(2-cyanoethyl)oxazolidines have been prepared and characterized by IR and 1H NMR spectra.The compounds have been tested as agents in flotation of lead-zinc ore.

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