41999-70-6

Basic information

• Product Name: 2-[(3-aminopropyl)methylamino]ethanol
• Synonyms: 2-[(3-aminopropyl)methylamino]ethanol;N-Methyl-N-(2-hydroxyethyl)-1,3-propanediamine;Ethanol, 2-[(3-aminopropyl)methylamino]- (6CI,7CI,9CI);AMINOPROPYLMONOMETHYLETHANOLAMINE;FENTAMINE APMMEA;(3-Aminopropyl)(2-hydroxyethyl)methylamine;N-(2-Hydroxyethyl)-N-methyl-1,3-propylenediamine;N-(3-Aminopropyl)-N-(2-hydroxyethyl)methylamine
• CAS NO: 41999-70-6
• Molecular Formula: C₆H₁₆N₂O
• Molecular Weight: 132.20404
• EINECS: 255-615-9
• Product Categories: AMINETERTIARY
• Mol File: 41999-70-6.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 229℃
• Flash Point: 92℃
• Appearance: /
• Density: 0.971
• Vapor Pressure: 0.014mmHg at 25°C
• Refractive Index: 1.4781
• PKA: 14.76±0.10(Predicted)
• CAS DataBase Reference: 2-[(3-aminopropyl)methylamino]ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(3-aminopropyl)methylamino]ethanol(41999-70-6)
• EPA Substance Registry System: 2-[(3-aminopropyl)methylamino]ethanol(41999-70-6)

Safety Data

• Hazardous Substances Data: 41999-70-6(Hazardous Substances Data)

Usage

General Description

"2-[(3-aminopropyl)methylamino]ethanol is a synthetic organic compound with the molecular formula C6H16N2O. It belongs to the category of organic compounds known as alpha amino acids and derivatives, compounds containing an amino group attached to the alpha carbon of a carboxylic acid group. It contains two amino (NH2) groups and one hydroxyl (alcohol, -OH) group, making the compound a bifunctional amine and alcohol. It features a blend of basic chemical traits of both amine and alcohol functional groups, which can influence its behavior and reactions. This chemical is typically used as a reagent or intermediate in chemical synthesis, coatings, biocides, or pharmaceutical products. The properties and applications of "2-[(3-aminopropyl)methylamino]ethanol" can vary widely depending on its specific formulation or the way it is combined with other substances. It, however, requires careful handling due to its potential toxic and corrosive nature.

InChI:InChI=1/C6H16N2O/c1-8(5-6-9)4-2-3-7/h9H,2-7H2,1H3

Upstream product

• 34508-82-2 monomethylethanolaminopropionitrile 
• 33759-44-3 3-<(2-hydroxyethyl)amino>propionitrile 
• 109-83-1 (2-hydroxyethyl)(methyl)amine 
• 107-13-1 acrylonitrile 

Downstream Products

• 31501-33-4 N-oleoylaminopropyl-N-hydroxyethyl-N-methylamine 
• 153075-23-1 N-oleoylaminopropyl-N-oleoyloxyethyl-N-methylamine 
• 4318-37-0 1-Methylhomopiperazine 

Relevant articles and documents

N,N,N'-trimethyl-N'-aminopropyldiaminoethylether

The invention provides two synthetic methods for technologically producing a novel polyurethane catalyst N,N,N'-trimethyl-N'-aminopropyldiaminoethylether. A method I is characterized by using trimethyldiaminoethylether as a raw material to react with acrylonitrile, then hydrogenating the product under the condition of catalysts including skeletal nickel, palladium-carbon, platinum-carbon, ruthenium-carbon, and the like, and carrying out separation, thus obtaining the target product. A method II is characterized by condensing dimethylethanolamine and N-methyl-N-aminopropylethanolamine and carrying out separation, thus obtaining the target product.

Synthesis and DNA-Sequence Selectivity of a Series of Mono- and Difunctional 9-Aminoacridine Nitrogen Mustards

The aim of this work was to identify nitrogen mustards that would react selectively with DNA, particularly in G-rich regions.A series of mono- and difunctional nitrogen mustards was synthesized in which the (2-chloroethyl)amino functions were connected to the N9 of 9-aminoacridine by way of a spacer chain consisting of two to six methylene units.The length of the spacer chain connecting the alkylating and putative DNA-intercalating groups was found to affect the preference for the alkylation of different guanine-N7 positions in a DNA sequence.All of the compounds reacted preferentially at G's that are followed by G as do most other types of nitrogen mustards, but the degree of selectivity was greater.The compounds reacted at much lower concentrations than were required for comparable reaction by mechlorethamine (HN2), consistent with initial noncovalent binding to DNA prior to guanine-N7 alkylation.The degree of DNA-sequance selectivity increased as the spacer-chain length decrease below four methylene units.Most strikingly, long spacer compounds reacted strongly at 5'-GT-3' sequences, whereas this reaction was almost completely suppressed when the spacer length was reduced to two or three methylenes.Mono- and difunctional compounds of a given spacer length showed no consistent difference in DNA-sequence preference.