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[1-(4-chlorophenyl)cyclohexyl]methanamine, also known as PCPr, is a psychoactive chemical belonging to the arylcyclohexylamine class. It is a derivative of phencyclidine (PCP) and is known to have hallucinogenic and dissociative properties. PCPr is a potent NMDA receptor antagonist, meaning it affects the neurotransmitter glutamate in the brain. It is often used recreationally for its mind-altering effects, and its long-term effects on the human body are not well understood. Due to its psychoactive nature, PCPr is a controlled substance in many countries and is considered illegal to possess, produce, or distribute without proper authorization.

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  • 342425-45-0 Structure
  • Basic information

    1. Product Name: [1-(4-chlorophenyl)cyclohexyl]methanamine
    2. Synonyms: [1-(4-chlorophenyl)cyclohexyl]methanamine
    3. CAS NO:342425-45-0
    4. Molecular Formula: C13H18ClN
    5. Molecular Weight: 223.74172
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 342425-45-0.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: [1-(4-chlorophenyl)cyclohexyl]methanamine(CAS DataBase Reference)
    10. NIST Chemistry Reference: [1-(4-chlorophenyl)cyclohexyl]methanamine(342425-45-0)
    11. EPA Substance Registry System: [1-(4-chlorophenyl)cyclohexyl]methanamine(342425-45-0)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 342425-45-0(Hazardous Substances Data)

342425-45-0 Usage

Uses

Used in Recreational Drug Use:
[1-(4-chlorophenyl)cyclohexyl]methanamine is used as a recreational drug for its hallucinogenic and dissociative effects on the user's mind. It alters the user's perception and experience, providing a unique and intense experience.
Used in Research and Development:
[1-(4-chlorophenyl)cyclohexyl]methanamine is used as a research chemical for studying the effects of NMDA receptor antagonists on the brain and neurotransmission. This helps scientists understand the mechanisms of action and potential therapeutic applications of similar compounds.
Used in Pharmaceutical Industry:
[1-(4-chlorophenyl)cyclohexyl]methanamine is used as a starting material or intermediate in the synthesis of other pharmaceutical compounds with potential therapeutic applications. Its properties as an NMDA receptor antagonist make it a valuable compound for further research and development in the field of psychopharmacology.

Check Digit Verification of cas no

The CAS Registry Mumber 342425-45-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,2,4,2 and 5 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 342425-45:
(8*3)+(7*4)+(6*2)+(5*4)+(4*2)+(3*5)+(2*4)+(1*5)=120
120 % 10 = 0
So 342425-45-0 is a valid CAS Registry Number.

342425-45-0Downstream Products

342425-45-0Relevant articles and documents

INDOLE CARBOXAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS

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Page/Page column 113, (2014/07/08)

The invention relates to indole carboxamide derivatives of formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10 and n are as defined in the description, their preparation and their use as pharmaceutically active compounds.

Discovery of N-methyl-1-(1-phenylcyclohexyl)methanamine, a novel triple serotonin, norepinephrine, and dopamine reuptake inhibitor

Shao, Liming,Hewitt, Michael C.,Wang, Fengjiang,Malcolm, Scott C.,Ma, Jianguo,Campbell, John E.,Campbell, Una C.,Engel, Sharon R.,Spicer, Nancy A.,Hardy, Larry W.,Schreiber, Rudy,Spear, Kerry L.,Varney, Mark A.

scheme or table, p. 1438 - 1441 (2011/04/16)

The current work discloses a novel cyclohexylarylamine chemotype with potent inhibition of the serotonin, norepinephrine, and dopamine transporters and potential for treatment of major depressive disorder. Optimized compounds 1 (SERT, NET, DAT, IC50 = 169, 85, 21 nM) and 42 (SERT, NET, DAT IC50 = 34, 295, 90 nM) were highly brain penetrant, active in vivo in the mouse tail suspension test at 30 mpk po and were not general motor stimulants.

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