344747-26-8Relevant articles and documents
Syntheses of 5-chlorouracils/thymines with 1-[phosphono(methyl/ difluoromethyl)]-1,2-unsaturated-moiety-substituted methyl groups at N(1) and human thymidine phosphorylase inhibitory activity
Birck, Matthew R.,Clinch, Keith,Gainsford, Graeme J.,Schramm, Vern L.,Tyler, Peter C.
experimental part, p. 823 - 838 (2009/08/14)
By attaching (methyl)- or (difluoromethyl)-phosphonate groups to the 1-positions of ethene, cyclopentene or benzene, and attaching 1-(methyl)-5-chlorouracil or 1-(methyl)thymine groups to the corresponding 2-positions, compounds 1 - 5 were prepared as pot