34522-69-5

Basic information

• Product Name: 5,7-DIBROMO-QUINOLINE
• Synonyms: 5,7-DIBROMO-QUINOLINE
• CAS NO: 34522-69-5
• Molecular Formula: C9H5Br2N
• Molecular Weight: 286.95
• Mol File: 34522-69-5.mol

Chemical Properties

• Boiling Point: 347.6°C at 760 mmHg
• Flash Point: 164°C
• Appearance: /
• Density: 1.923g/cm³
• Vapor Pressure: 0.000107mmHg at 25°C
• Refractive Index: 1.698
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 5,7-DIBROMO-QUINOLINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5,7-DIBROMO-QUINOLINE(34522-69-5)
• EPA Substance Registry System: 5,7-DIBROMO-QUINOLINE(34522-69-5)

Safety Data

• Hazardous Substances Data: 34522-69-5(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5,7-DIBROMO-QUINOLINE is used as a building block for the synthesis of various pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical industry, 5,7-DIBROMO-QUINOLINE serves as a key component in the production of agrochemicals, aiding in the creation of effective pest control and crop protection solutions.
Used in Dye Production:
5,7-DIBROMO-QUINOLINE is utilized in the preparation of fluorescent dyes, which have applications in various fields such as bioimaging, diagnostics, and other specialized industries.
Used in Organic Compound Synthesis:
5,7-DIBROMO-QUINOLINE also acts as a precursor in the production of other organic compounds, further expanding its applications across different chemical and industrial sectors.

InChI:InChI=1/C9H5Br2N/c10-6-4-8(11)7-2-1-3-12-9(7)5-6/h1-5H

Upstream product

• 626-40-4 3,5-dibromoaniline 
• 56-81-5 glycerol 

Downstream Products

• 1378860-76-4 7-bromo-5-methoxy-quinoline 
• 1126824-44-9 5-bromo-7-methoxy-quinoline 
• 36107-02-5 5,7-dibromo-8-aminoquinoline 
• 34522-73-1 5,7-dibromo-8-nitro-quinoline 

Relevant articles and documents

Synthesis method of 7-bromo-5-methoxyquinoline

The invention discloses a synthesis method of 7-bromo-5-methoxyquinoline, which comprises the following steps: carrying out Skraup condensation reaction on 3, 5-dibromoaniline serving as a raw material and glycerol to obtain 5, 7-dibromoquinoline, reacting with sodium methoxide to obtain 5-bromo-7-methoxyquinoline and 7-bromo-5-methoxyquinoline, and finally carrying out column chromatography purification and separation to obtain the 7-bromo-5-methoxyquinoline. The method overcomes the defects of low yield, microwave condition requirement, difficulty in post-treatment, difficulty in amplification and the like in the existing synthesis process. According to the synthetic method, the 3, 5-dibromoaniline is used as a raw material, the process selection is reasonable, the raw material cost is low, the raw materials are simple and easy to obtain, the operation and post-treatment are convenient, the total yield is high, a highly toxic reagent is not used, amplification is easy, and large-scale production can be carried out.

ANTAGONISTS OF PROSTAGLANDIN EP3 RECEPTOR

Provided herein are antagonists la or lb of prostaglandin EP3 receptor, processes to make said antagonists, and methods comprising administering said antagonists to a mammal in need thereof. (Formula I)