348165-62-8 Usage
Uses
Used in Pharmaceutical Industry:
(2R, 4S)-4-Hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester is used as an intermediate in the synthesis of pharmaceutical compounds for its unique structural features and reactivity. Its specific spatial arrangement and functional groups make it a valuable building block in the development of new drugs with potential therapeutic applications.
Used in Chemical Synthesis:
In the field of organic chemistry, (2R, 4S)-4-Hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester serves as a versatile synthetic building block. Its unique structure allows for various chemical reactions, enabling the synthesis of a wide range of organic compounds with different properties and applications.
Used in Research and Development:
(2R, 4S)-4-Hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester is utilized in research and development for studying its properties, reactivity, and potential applications. Scientists and researchers explore its behavior in different chemical reactions and environments to gain insights into its potential uses and limitations.
Used in Material Science:
In material science, (2R, 4S)-4-Hydroxy-2-methyl-pyrrolidine-1-carboxylic acid tert-butyl ester may be employed in the development of new materials with specific properties. Its unique structure and functional groups can contribute to the creation of materials with tailored characteristics, such as improved stability, reactivity, or selectivity in various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 348165-62-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,4,8,1,6 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 348165-62:
(8*3)+(7*4)+(6*8)+(5*1)+(4*6)+(3*5)+(2*6)+(1*2)=158
158 % 10 = 8
So 348165-62-8 is a valid CAS Registry Number.
348165-62-8Relevant articles and documents
TRANS-3,5-DISUBSTITUTEDPYRROLIDINE: ORGANOCATALYST FOR anti-MANNICH REACTIONS
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Page/Page column 24, (2010/11/27)
A compound of Formula I is disclosed, in which R is a substituent containing a hydrogen bond-forming atom within three atoms from the ring carbon to which the substituent is bonded; X is CH2, O, S or NR1, wherein R1 is a hydrocarbyl group or an amino-protecting group having one to about 18 carbon atoms; R2 is hydrido or a hydrocarbyl group containing one to about twelve carbon atoms; and R3 is hydrido or methyl, but both R2 and R3 are not hydrido when X is CH2 A molecule of Formula I and those in which R2 and R3 can both be hydrido (Formula X) functions as a catalyst in a Mannich reaction to asymmetrically form β-aminoaldehyde or β-aminoketone diastereomeric products having two chiral centers on adjacent carbon atoms and in which the anti-diastereomers are in excess over the syn-diastereomers. Methods for carrying out those syntheses are also disclosed.
Direct asymmetric anti-Mannich-type reactions catalyzed by a designed amino acid
Mitsumori, Susumu,Zhang, Haile,Cheong, Paul Ha-Yeon,Houk,Tanaka, Fujie,Barbas, Carlos F.
, p. 1040 - 1041 (2007/10/03)
The development of catalysts for Mannich-type reactions that afford anti-products with excellent diastereo- and enantioselectivities under mild conditions and low catalyst loadings (1-5 mol %) is reported. Based on principles gained from the study of (S)-
