351226-57-8 Usage
Uses
Used in Pharmaceutical Synthesis:
2-(Chloromethyl)-1H-benzimidazole-5-carboxylic acid hydrochloride is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to be incorporated into the molecular structures of potential drugs. Its chloromethyl group and carboxylic acid functionality allow for versatile chemical reactions, facilitating the creation of new drug candidates.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, 2-(Chloromethyl)-1H-benzimidazole-5-carboxylic acid hydrochloride is utilized as a building block for the development of new compounds with potential therapeutic properties. Its unique structure and reactivity make it a valuable tool for designing molecules that can target specific biological pathways or receptors, contributing to the advancement of drug discovery.
Used in Drug Development:
2-(Chloromethyl)-1H-benzimidazole-5-carboxylic acid hydrochloride is employed in drug development as a precursor to create bioactive molecules with potential applications in treating various diseases and conditions. Its chemical properties enable the formation of diverse compounds that can be optimized for efficacy, safety, and pharmacokinetic properties, making it an essential component in the development pipeline of new therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 351226-57-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,1,2,2 and 6 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 351226-57:
(8*3)+(7*5)+(6*1)+(5*2)+(4*2)+(3*6)+(2*5)+(1*7)=118
118 % 10 = 8
So 351226-57-8 is a valid CAS Registry Number.
351226-57-8Relevant articles and documents
Synthesis, characterization and antibacterial evaluation of some novel benzimidazole derivatives containing 1,3,4-thiadiazole moiety
Redayan, Muayed Ahmed,Ali, Wassan Baqir,Mohammed, Ahmed Mudhafar
, p. 3138 - 3143 (2018/01/17)
A series of novel 5-amino-1,3,4-thiadiazole-2-thiol and 1,3,4-thiadiazole-2,5-dithiol derivatives of benzimidazole were synthesized through nucleophilic substitution reaction of 5-substituted-2-(chloromethyl)-1H-benzimidazole, structures of the synthesized compounds were proved by spectral methods of analysis (FT-IR, 1H and 13C NMR). All the target compounds were screened for their antibacterial activity toward gram-negative (E.coli, P. aeruginosa) and Gram-positive (B. subtilis, S. aureus) bacteria, most of the synthesized derivatives exhibited good to moderate activity toward both Gram-positive (B. subtilis, S. aureus) and Gram-negative (E.coli, P. aeruginosa) bacteria.
Benzimidazole compounds and antiviral uses thereof
-
, (2008/06/13)
The present invention relates to novel benzimidazole compounds that have useful antiviral activity. More specifically, the invention encompasses benzimidazole compounds that inhibit membrane fusion associated events such as viral transmission, reduce vira
