352445-68-2

Basic information

• Product Name: 4-(3,9-diazaspiro[5.5]undecan-3-yl)benzonitrile
• Synonyms: 4-(3,9-diazaspiro[5.5]undecan-3-yl)benzonitrile
• CAS NO: 352445-68-2
• Molecular Formula: C₁₆H₂₁N₃
• Molecular Weight: 255.35804
• Mol File: 352445-68-2.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-(3,9-diazaspiro[5.5]undecan-3-yl)benzonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(3,9-diazaspiro[5.5]undecan-3-yl)benzonitrile(352445-68-2)
• EPA Substance Registry System: 4-(3,9-diazaspiro[5.5]undecan-3-yl)benzonitrile(352445-68-2)

Safety Data

• Hazardous Substances Data: 352445-68-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
4-(3,9-diazaspiro[5.5]undecan-3-yl)benzonitrile is used as a research compound for developing new pharmaceutical agents with antipsychotic and anticonvulsant properties. Its unique structure and biological activities make it a promising candidate for the discovery of novel therapeutic agents.
Used in Agrochemical Research:
4-(3,9-diazaspiro[5.5]undecan-3-yl)benzonitrile is used as a research compound in agrochemical research to explore its potential as a new active ingredient for pest control and crop protection. Its diverse biological activities may contribute to the development of innovative agrochemicals with improved efficacy and safety profiles.
Used in Synthetic Chemistry:
4-(3,9-diazaspiro[5.5]undecan-3-yl)benzonitrile is used as a target compound for synthetic chemists to study and develop new methodologies for constructing complex molecular frameworks. Its spirocyclic structure offers opportunities for the synthesis of novel compounds with potential applications in various fields.

Upstream product

• 1194-02-1 4-fluorobenzonitrile 
• 173405-78-2 tert-butyl 3,9-diazaspiro[5.5]undecane-3-carboxylate 
• 623-00-7 4-bromobenzenecarbonitrile 

Relevant articles and documents

Synthesis and antitubercular evaluation of reduced lipophilic imidazo[1,2-a]pyridine-3-carboxamide derivatives

A series of reduced lipophilic N-benzylic imidazo[1,2-a]pyridine carboxamides (IPAs) with various side chains were designed and synthesized as new anti-TB agents in this work. Five derivatives A2, A3, A4, B1 and B9 exhibit excellent in vitro activity (MIC: 0-∞ and Cmax than Q203 and PBTZ169, suggesting its promising potential to be a lead compound for future antitubercular drug discovery.

Spirocyclic nonpeptide glycoprotein IIb-IIIa antagonists. Part 1: Design of potent and specific 3,9-diazaspiro[5.5]undecanes

The synthesis and biological activity of novel glycoprotein IIb-IIIa antagonists containing the 3,9-diazaspiro[5.5]undecane nucleus are described. The potent activity of these compounds as platelet aggregation inhibitors demonstrates the utility of the spirocyclic structures as a central template for nonpeptide RGD mimics.