352524-56-2 Usage
Uses
Used in Pharmaceutical Industry:
(S)-3-(4-Acetylphenyl)-4-benzyloxazolidin-2-one is used as a chiral building block for the synthesis of biologically active molecules and pharmaceutical drugs. Its unique structure allows for the creation of a wide range of compounds with potential therapeutic applications.
Used in Organic Synthesis:
In the field of organic synthesis, (S)-3-(4-Acetylphenyl)-4-benzyloxazolidin-2-one is utilized as a valuable intermediate. Its properties facilitate the development of new chemical compounds and contribute to advancements in material science.
Used in Drug Discovery:
(S)-3-(4-ACETYLPHENYL)-4-BENZYLOXAZOLIDIN-2-ONE is also used in drug discovery, where its potential pharmaceutical applications are explored. Its unique structure and properties make it a promising candidate for the development of new drugs.
Used in Antiviral and Antifungal Applications:
(S)-3-(4-Acetylphenyl)-4-benzyloxazolidin-2-one has been studied for its potential antiviral and antifungal activities, making it a candidate for use in the development of treatments for various viral and fungal infections.
Check Digit Verification of cas no
The CAS Registry Mumber 352524-56-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,5,2,5,2 and 4 respectively; the second part has 2 digits, 5 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 352524-56:
(8*3)+(7*5)+(6*2)+(5*5)+(4*2)+(3*4)+(2*5)+(1*6)=132
132 % 10 = 2
So 352524-56-2 is a valid CAS Registry Number.
InChI:InChI=1/C18H17NO3/c1-13(20)15-7-9-16(10-8-15)19-17(12-22-18(19)21)11-14-5-3-2-4-6-14/h2-10,17H,11-12H2,1H3/t17-/m0/s1
352524-56-2Relevant articles and documents
Palladium-catalyzed synthesis of N-aryloxazolidinones from aryl chlorides
Ghosh, Arun,Sieser, Janice E.,Riou, Maxime,Cai, Weiling,Rivera-Ruiz, Luis
, p. 2207 - 2210 (2007/10/03)
(Matrix presented) An efficient method for intermolecular N-arylation of oxazolidinones using Pd2dba3 and various phosphine ligands in the presence of a weak base is reported. The conditions allow the use of cheaper aryl chlorides containing functionalities such as enolizable ketones, amides, etc., which would be incompatible with other coupling methods. The coupling reaction can be used to prepare enantiopure N-aryl β-amino alcohols. Depending on the stereoelectronic nature of the aryl chloride, careful choice of ligand was necessary for the success of these reactions.
Synthesis of N-arylated oxazolidinones via a palladium catalyzed cross coupling reaction. Application to the synthesis of the antibacterial agent Dup-721
Madar, David J.,Kopecka, Hana,Pireh, Daisy,Pease, Jonathan,Pliushchev, Marina,Sciotti, Richard J.,Wiedeman, Paul E.,Djuric, Stevan W.
, p. 3681 - 3684 (2007/10/03)
A method for the intermolecular coupling of aryl bromides and oxazolidinones is described. Application to intermediates useful for the preparation of a known class of antibacterial agent and the synthesis of the known antibacterial oxazolidinone Dup-721 are described.
