35434-71-0 Usage
Uses
Used in Pharmaceutical Industry:
Trimethyl-d8-amine is used as a building block for the synthesis of various pharmaceuticals. Its deuterated form provides unique properties that can enhance the stability, solubility, and bioavailability of the resulting compounds, making it a valuable component in drug development.
Used in Pesticide Industry:
In the pesticide industry, trimethyl-d8-amine is utilized as a building block for the synthesis of various pesticides. Its deuterated nature can improve the effectiveness and selectivity of the resulting pesticides, leading to more efficient and targeted pest control.
Used in Polymer Industry:
Trimethyl-d8-amine is used as a building block in the synthesis of polymers. Its deuterated form can contribute to the development of polymers with improved mechanical, thermal, and chemical properties, expanding the range of applications for these materials.
Used as a Solvent in Chemical Reactions:
Trimethyl-d8-amine is used as a solvent for various chemical reactions. Its unique properties can facilitate specific reaction pathways, improve reaction rates, and enhance the yield of desired products, making it a valuable component in many chemical processes.
Used as a Precursor for Quaternary Ammonium Compounds:
Trimethyl-d8-amine serves as a precursor for the production of quaternary ammonium compounds. Its deuterated form can provide unique characteristics to the resulting compounds, such as improved solubility, stability, and reactivity, broadening the scope of applications for these materials in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 35434-71-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,5,4,3 and 4 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 35434-71:
(7*3)+(6*5)+(5*4)+(4*3)+(3*4)+(2*7)+(1*1)=110
110 % 10 = 0
So 35434-71-0 is a valid CAS Registry Number.
35434-71-0Relevant articles and documents
Nonadditivity of secondary deuterium isotope effects on basicity of trimethylamine
Perrin, Charles L.,Dong, Yanmei
supporting information; experimental part, p. 11143 - 11148 (2009/02/05)
Secondary deuterium isotope effects (IEs) on basicities of isotopologues of trimethylamine have been accurately measured by an NMR titration method applicable to a mixture. Deuteration definitely increases the basicity, by ～0.021 in the ΔpK per D. The IE is attributed to the lowering of the CH stretching frequency and zero-point energy by delocalization of the nitrogen lone pair into the C-H antibonding orbital. Because this depends on the dihedral angle between the lone pair and the C-H, a further consequence is a preference for conformations with H antiperiplanar to the lone pair and D gauche. This leads to a predicted nonadditivity of IEs, which is confirmed experimentally. It is found that the decrease in basicity, per deuterium, increases with the number of deuteriums. The nonadditivity of IEs is a violation of the widely assumed Rule of the Geometric Mean.
