360061-99-0Relevant articles and documents
Novel sulfonate derivatives: Potent antimitotic agents
Gwaltney II, Stephen L.,Imade, Hovis M.,Li, Qun,Gehrke, Laura,Credo,Warner, Robert B.,Lee, Jang Yun,Kovar, Peter,Frost, David,Ng, Shi-Chung,Sham, Hing L.
, p. 1671 - 1673 (2007/10/03)
The synthesis and biological evaluation of novel sulfonate analogues of E-7010 are reported. Several of the compounds are potent inhibitors of cell proliferation and tubulin polymerization. Importantly, these compounds are also active against P-glycoprote