98-68-0Relevant articles and documents
N-ARYL SULFONAMIDE DERIVATIVES AS VACCINE ADJUVANT
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Page/Page column 101-102, (2021/02/26)
Bis-aryl sulfonamide compounds and methods of using those compounds, e.g., in a method of enhancing or prolonging an immune response, are provided. For example, the compounds may be employed with a vaccine and optionally at least one other adjuvant and/or one or more TLR ligands, at least one MAP kinase inhibitor, or any combination thereof.
Sulfonimidesversusketosulfonamides as epoxidized imidazolium counterions: Towards a new generation of ionic liquid monomers
Chardin,Durand,Jarsalé,Rouden,Livi,Baudoux
supporting information, p. 2953 - 2957 (2021/02/26)
The design of novel ionic liquid monomers with attractive properties represents a real challenge in the field of poly(ionic liquid)s (PILs). Here, we describe a comparative study of the synthesis of original PIL precursors from various sulfonimides or ketosulfonamides as unprecedented counteranions of imidazolium ILs. These salts were submitted to the Prilezhaev reaction and a first insight into the intrinsic properties of these new epoxy monomers was unveiled, in particular the thermal stability of these advanced epoxy salts by comparison with traditional counterions.
Facile synthesis of sulfonyl chlorides/bromides from sulfonyl hydrazides
Chen, Rongxiang,Xu, Shaohong,Shen, Fumin,Xu, Canran,Wang, Kaikai,Wang, Zhanyong,Liu, Lantao
, (2021/09/20)
A simple and rapid method for efficient synthesis of sulfonyl chlorides/bromides from sulfonyl hydrazide with NXS (X = Cl or Br) and late-stage conversion to several other functional groups was described. A variety of nucleophiles could be engaged in this transformation, thus permitting the synthesis of complex sulfonamides and sulfonates. In most cases, these reactions are highly selective, simple, and clean, affording products at excellent yields.