361460-40-4

Usage

Uses

Used in Pharmaceutical Industry:
2(3H)-Furanone, dihydro-5-[(1S,3S)-3-[[4-Methoxy-3-(3-Methoxypropoxy)phenyl]Methyl]-4-Methyl-1-[(phenylMethyl)aMino]pentyl]-3-(1-Methylethyl)-, (3S,5S)is used as a pharmaceutical compound for its potential therapeutic properties. The presence of various functional groups and isomer configurations allows it to interact with biological targets, making it a promising candidate for the development of new drugs.
Used in Organic Synthesis:
In the field of organic synthesis, 2(3H)-Furanone, dihydro-5-[(1S,3S)-3-[[4-Methoxy-3-(3-Methoxypropoxy)phenyl]Methyl]-4-Methyl-1-[(phenylMethyl)aMino]pentyl]-3-(1-Methylethyl)-, (3S,5S)serves as a key intermediate or building block for the synthesis of more complex organic molecules. Its unique structure and functional groups enable the formation of new chemical entities with potential applications in various industries.
Used in Chemical Research:
2(3H)-Furanone, dihydro-5-[(1S,3S)-3-[[4-Methoxy-3-(3-Methoxypropoxy)phenyl]Methyl]-4-Methyl-1-[(phenylMethyl)aMino]pentyl]-3-(1-Methylethyl)-, (3S,5S)is utilized in chemical research to study its properties, reactivity, and potential applications. Researchers can explore its behavior in various chemical reactions, as well as its interactions with other molecules, to gain insights into its potential uses and limitations.

Upstream product

• 361460-39-1 N-Benzyl-N-{(1S,3S)-1-((2S,3S,5S,7S,9S)-9-isopropyl-3,4-dimethyl-2-phenyl-1,6-dioxa-4-aza-spiro[4.4]non-7-yl)-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-hydroxylamine 
• 900811-48-5 3(S)-isopropyl-5(S)-{1(S)-amino-3(S)-isopropyl-4-[4-methoxy-3-(3-methoxypropyloxy)-phenyl]-butyl}-tetrahydrofuran-2-one 
• 100-52-7 benzaldehyde 
• 1206809-42-8 C₃₂H₄₅NO₅ 
• 656241-17-7 (2S,5R)-2,5-dihydro-3,6-dimethoxy-2-{(2S)-2-{[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl}-3-methylbutyl}-5-(1-methylethyl)pyrazine 
• 656241-36-0 methyl (2S,4S)-2-amino-4-[4-methoxy-3-(3-methoxypropoxy)benzyl]-5-methylhexanoate 
• 172900-69-5 (R)-4-(2-(bromomethyl)-3-methylbutyl)-1-methoxy-2-(3-methoxypropoxy)benzene 
• 900811-49-6 {(1S,3S)-1-((S)-4-Isopropylidene-5-oxo-tetrahydro-furan-2-yl)-3-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-4-methyl-pentyl}-carbamic acid benzyl ester 
• 900811-42-9 pyridin-4-yl (2S,4S)-2-[[(phenylmethoxy)carbonyl]amino]-4-methoxy-3-(3-methoxypropoxy)-γ-(1-methylethyl)benzenepentanethioate 
• 900811-43-0 (5S,7S)-5-Benzyloxycarbonylamino-7-[4-methoxy-3-(3-methoxy-propoxy)-benzyl]-8-methyl-4-oxo-nonanoic acid methyl ester 
• 900811-45-2 phenylmethyl [(1S,3S)-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-[(2S)-tetrahydro-5-oxo-2-furanyl]pentyl]carbamate 
• 900811-41-8 (2S,4S)-2-[[(phenylmethoxy)carbonyl]amino]-4-methoxy-3-(3-methoxypropoxy)-γ-(1-methylethyl)benzenepentanoic acid 
• 900811-40-7 methyl (2S,4S)-2-[[(phenylmethoxy)carbonyl]amino]-4-methoxy-3-(3-methoxypropoxy)-γ-(1-methylethyl)benzenepentanoate 
• 900811-48-5 (5S)-dihydro-5-[(1S,3S)-3-[[4-methoxy-3-(3-methoxypropoxy)phenyl]methyl]-4-methyl-1-aminopentyl]-3-(1-methylethyl)-2(3H)-furanone 

Relevant academic research and scientific papers

Iron triflate catalyzed reductive amination of aldehydes using sodium borohydride

An efficient and convenient procedure for the reductive amination of aldehydes using NaBH4 in the presence of catalytic amount of Fe(OTf)3 is described.

SYNTHESIS ROUTES TO 2(S),4(S),5(S),7(S)-2,7-DIALKYL-4-HYDROXY-5-AMINO-8-ARYL-OCTANOYL AMIDES

The invention relates to a process for the preparation of compounds that are important building blocks in convergent synthesis routes to 2(S),4(S),5(S),7(S)-2,7-dialkyl-4-hydroxy-5-amino-8-aryl-octanoyl amides or pharmaceutically acceptable salts thereof, such as the compound Aliskiren, and to a process for the preparation of these octanoyl amides, comprising reacting said building block.

Formal total synthesis of the potent renin inhibitor aliskiren: Application of a SmI2-promoted acyl-like radical coupling

A formal total synthesis of the potent renin inhibitor aliskiren is disclosed exploiting an alternative coupling strategy recently developed by this laboratory for the preparation of the hydroxyethylene isostere-based class of protease inhibitors. The thi

Process for the preparation of aryloctanoyl amides

Compounds of formula IwhereinR1is for example 3-methoxyprop-3-yloxy, R2is for example methoxy, R3and R4are in each case for example isopropyl, and R5is H2NC(O)-[C(CH3)2]-CH2-, are obtainable by reaction of compounds of formula IV(IV) with a metal organic derivative of 1-(3-R1-4-R2-phen-1-yl)-2-R3-3-halogen propanes to form a compound of formula VI,followed by removal of the pseudoephedrine protecting group and the OH group, reaction of the resulting lactone with an amine R5-NH2and removal of protecting group Z.