362049-51-2

Basic information

• Product Name: METHYL 4-HYDROXYBENZOATE-2,3,5,6-D4
• Synonyms: METHYL P-HYDROXYBENZOATE-2,3,5,6-D4;METHYL 4-HYDROXYBENZOATE-2,3,5,6-D4;Methyl Paraben-d4;Methyl 4-Hydroxybenzoate--d4
• CAS NO: 362049-51-2
• Molecular Formula: C₈H₈O₃
• Molecular Weight: 156.17
• Mol File: 362049-51-2.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Refrigerator
• Solubility: DMSO (Slightly), Methanol (Slightly, Heated)
• CAS DataBase Reference: METHYL 4-HYDROXYBENZOATE-2,3,5,6-D4(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4-HYDROXYBENZOATE-2,3,5,6-D4(362049-51-2)
• EPA Substance Registry System: METHYL 4-HYDROXYBENZOATE-2,3,5,6-D4(362049-51-2)

Safety Data

• Hazardous Substances Data: 362049-51-2(Hazardous Substances Data)

Usage

Uses

Used in Food Industry:
METHYL 4-HYDROXYBENZOATE-2,3,5,6-D4 is used as a preservative for maintaining the freshness and quality of various food products. It helps prevent the growth of bacteria, mold, and other microorganisms, ensuring the safety and longevity of the products.
Used in Beverage Industry:
In the beverage industry, METHYL 4-HYDROXYBENZOATE-2,3,5,6-D4 is used as a preservative to extend the shelf life of drinks and prevent spoilage. It is particularly useful in products that are prone to microbial contamination, such as fruit juices, soft drinks, and alcoholic beverages.
Used in Cosmetics Industry:
METHYL 4-HYDROXYBENZOATE-2,3,5,6-D4 is used as a preservative in the cosmetics industry to prevent the growth of harmful microorganisms in products like lotions, creams, and makeup. It helps maintain the product's stability and ensures that it remains safe for use over time.

Upstream product

• 67-56-1 methanol 
• 152404-47-2 [2′,3′,5′,6′-D4]-4′-hydroxybenzoic acid 
• 99-96-7 4-hydroxy-benzoic acid 
• 99-76-3 methyl 4-hydroxylbenzoate 

Relevant articles and documents

Efficient continuous-flow HD exchange reaction of aromatic nuclei in D2O/2-PrOH mixed solvent in a catalyst cartridge packed with platinum on carbon beads

Herein, a continuous-flow deuteration methodology for various aromatic compounds is developed based on heterogeneous platinum-catalyzed hydrogen-deuterium exchange. The reaction entails the transfer of a substrate dissolved in a mixed solvent of 2-propanol and deuterium oxide into a catalyst cartridge packed with platinum on carbon beads (Pt/CB). Pt/ CB could be continuously used without significant deterioration of catalyst activity for at least 24 h. Deuteration proceeded within 60 s of the substrate solutions being passed through the Pt/CB layer in the Pt/CB-packed cartridge.

Surface-Deactivated Core–Shell Metal–Organic Framework by Simple Ligand Exchange for Enhanced Size Discrimination in Aerobic Oxidation of Alcohols

Metal–organic frameworks (MOFs) are an attractive catalyst support for stable immobilization of the active sites in their scaffold due to the high tunability of organic ligands. The active site-functionalized ligands can be easily employed to construct MOFs as porous heterogeneous catalysts. However, the existence of active sites on the external surfaces as well as internal pores of MOFs seriously impedes the selective reaction in the pore. Herein, through a simple post-synthetic ligand exchange (PSE) method we synthesized surface-deactivated (only core-active) core–shell-type MOF catalysts, which contain 2,2,6,6-tetramethylpiperidin-1-yl)oxyl (TEMPO) groups on the ligand as active sites for aerobic oxidation of alcohols. The porous but catalytically inactive shell ensured the size-selective permeability by sieving effects and induced all reactions to take place in the pores of the catalytically active core. Because PSE is a facile and universal approach, this can be rapidly applied to a variety of MOF-based catalysts for enhancing reaction selectivity.

Synthesis method of paraben compounds marked by stable isotope 13C or D

The invention relates to a synthesis method of paraben compounds marked by a stable isotope 13C or D. In the method, p-hydroxybenzoic acid, which is marked by the stable isotope 13C or D, and an alcohol compound are employed as raw materials for preparing the paraben compounds under the effect of an acidic catalyst p-toluenesulfonic acid. Compared with a synthesis process of the paraben compounds in natural abundance, the method is free of isotope dilution during the reaction process, has mild reaction conditions and high utilization rate on the isotopes. The paraben compounds marked by the stable isotope 13C or D, after separation and purification, are more than 99% in chemical purity and are more than 99 atom% in isotope abundance.