363152-96-9Relevant articles and documents
Electrolytic partial fluorination of organic compounds. 83. Anodic fluorination of N-substituted pyrroles and its synthetic applications to gem-difluorinated heterocyclic compounds
Tajima, Toshiki,Nakajima, Atsushi,Fuchigami, Toshio
, p. 1436 - 1441 (2007/10/03)
Anodic fluorination of N-substituted pyrroles was carried out in MeCN containing supporting fluoride salts such as Et3N-nHF (n = 2-5) and Et4NF-4HF with use of platinum electrodes under constant current conditions. Anodic fluorinatio
A facile synthesis of gem-difluorinated heterocyclic compounds using anodic fluorination of 2-cyano-1-methylpyrrole as a key step
Tajima, Toshiki,Fuchigami, Toshio
, p. 2597 - 2600 (2007/10/03)
Anodic fluorination of 2-cyano-1-methylpyrrole 1 using Et3N·5HF in an undivided cell provided 5,5-difluoro-1-methyl-3-pyrrolin-2-one (5a). The Diels-Alder reaction of 5a with various dienes was successfully carried out to provide gem-difluorina
Electrolytic partial fluorination of organic compounds. Part 48: Anodic fluorination of 2-cyano-1-methylpyrrole
Tajima, Toshiki,Ishii, Hideki,Fuchigami, Toshio
, p. 4857 - 4860 (2007/10/03)
Anodic fluorination of 2-cyano-1-methylpyrrole using Et3N·2HF in an undivided cell provided the corresponding 5-fluoropyrrole and 2,5,5-trifluoro-1-methyl-3-pyrrolin-2-carbonitrile while the use of Et3N·3HF afforded selectively the latter product, which was readily hydrolyzed to isolable 5,5-difluoro-1-methyl-3-pyrroline-2-one. This is the first report of successful anodic fluorination of a pyrrole derivative.