34884-10-1Relevant academic research and scientific papers
Substituted thiazole derivatives useful as platelet aggregation inhibitors
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, (2008/06/13)
This invention relates to substituted thiazole derivatives of the following general formula, the substituent groups of which are as defined herein: STR1 These compounds are useful as inhibitors of platelet aggregation and inhibitors of adhesion molecules and may be provided in pharmaceutical compositions and in methods of treating reperfusion thrombosis injury in patients.
STUDIES ON DIMETHYLHYDRAZONES OF HETEROARYL ALDEHYDES. THE REACTIVITY OF 2-FORMYLFURAN, 2-FORMYLTHIOPHENE AND 1-METHYL-2-FORMYLPYRROLE N,N-DIMETHYLHYDRAZONES WITH METHYL PROPIOLATE AND DIETHYL AZODICARBOXYLATE
Abarca, Belen,Ballesteros, Rafael,Gonzalez, Eugenia,Sancho, Pedro,Sepulveda, Jose,Soriano, Concepcion
, p. 1811 - 1817 (2007/10/02)
The title hydrazones react with methyl propiolate giving the new 2-heteroarylpyridines (4, 5 and 6).The reaction with diethyl azodicarboxylate gives 1:1 Michael adducts except with formylthiophene hydrazone that gives the compound (14) a novel type of 1:1 adduct.
