363166-79-4

Basic information

• Product Name: 2,6-Diisopropylphenylboronic acid
• Synonyms: 2,6-Diisopropylphenylboronic acid;2-(3-isopropylphenyl)propylboronic acid
• CAS NO: 363166-79-4
• Molecular Formula: C₁₂H₁₉BO₂
• Molecular Weight: 206.08906
• Mol File: 363166-79-4.mol

Chemical Properties

• Melting Point: 167-172°C
• Boiling Point: 327.5±52.0 °C(Predicted)
• Appearance: /
• Density: 0.99±0.1 g/cm3(Predicted)
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• PKA: 8.74±0.58(Predicted)
• CAS DataBase Reference: 2,6-Diisopropylphenylboronic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-Diisopropylphenylboronic acid(363166-79-4)
• EPA Substance Registry System: 2,6-Diisopropylphenylboronic acid(363166-79-4)

Safety Data

• WGK Germany: nwg
• Hazardous Substances Data: 363166-79-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
2,6-Diisopropylphenylboronic acid is used as a building block for the creation of complex molecules, facilitating the synthesis of a wide range of organic compounds.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2,6-Diisopropylphenylboronic acid is utilized in the development of pharmaceuticals, contributing to the design and synthesis of new drug candidates.
Used in Chemical Biology Research:
2,6-Diisopropylphenylboronic acid also serves as a tool in chemical biology research, enabling the exploration of biological processes and the interaction of molecules with biological targets.
Used in Cross-Coupling Reactions:
2,6-Diisopropylphenylboronic acid is employed in cross-coupling reactions, such as the Suzuki-Miyaura coupling, to form carbon-carbon bonds, which are crucial for the synthesis of various organic compounds.
Used in Other Organic Transformations:
2,6-Diisopropylphenylboronic acid shows potential in various other organic transformations, further expanding its utility in the synthesis of a diverse array of chemical products.

Upstream product

• 688-74-4 boric acid tributyl ester 
• 57190-17-7 2-bromo-1,3-diisopropylbenzene 
• 121-43-7 Trimethyl borate 

Downstream Products

• 1395093-64-7 3-(2,6-diisopropylphenyl)-11-methoxyimidazo[1,2-f]phenanthridine 

Relevant articles and documents

2,6-diisopropyl benzene boric acid derivatives an pharmaceutical use thereof

The invention relates to a type of 2,6-diisopropyl benzene boric acid derivatives and pharmaceutical use thereof. The structure of the derivatives is accordant with a general formula shown in the description, wherein R1 represents -H or -CH(CH3)2. The drugs are sensitive to free radicals, and a large number of free radicals exist at ischemic parts, so that the drugs are capable of releasing diprivan or analogs of diprivan at the ischemic parts, are capable of well protecting ischemic injury and have a neuroprotective effect better than that of diprivan. The derivatives can be applied to the preparation of drugs for treating the ischemic injury.

Luminescent Pt(ii) complexes bearing dual isoquinolinyl pyrazolates: Fundamentals and applications

A series of four Pt(ii) metal complexes with trans-arranged isoquinolinyl azolates have been prepared, [Pt(Lx)2], x = 1-4, (1-4). The associated chelates possess various substituents; namely: one t-butyl (But) at the 6-position (L1), two But groups at the 5,7-positions (L2), one dip (2,6-di-isopropylphenyl) group at the 6-position (L3), and a single dip group at the 4-position of the 1-isoquinolinyl fragment (L4), respectively. Crystal structures of 1 and 4 were determined to shed light on the relationship of photophysics and packing arrangements. Their photophysical properties were measured and compared, for which the solid-state emission spectra of 2 and 4 are nearly identical to the solution spectra of all the Pt(ii) complexes, showing the formation of isolated molecular entities. In contrast, the Pt(ii) complexes 1 and 3 are found to be sensitive to their morphological states and external stimulus. This is confirmed by the gradual red-shifting of the emission with increasing concentration in the PMMA matrix, and the eventual formation of the broadened, metal-metal-to-ligand charge transfer (MMLCT) emission, by (i) wetting with acetone and drying in air, or (ii) grinding with a mortar and pestle, respectively. Organic light-emitting diodes (OLEDs) were also fabricated using multiple layered architecture and lowered doping concentration (e.g. 8 wt%), the latter is for avoiding dopant aggregation in the emitting layer. The associated OLED performances (i.e. ηmax = 11.5%, 8.5%, and 11.2% for 1, 2 and 3) confirmed their suitability and potential as dopants for phosphorescent OLEDs.

Structure-based approach to the development of potent and selective inhibitors of dihydrofolate reductase from Cryptosporidium

Cryptosporidiosis is an emerging infectious disease that can be life-threatening in an immune-compromised individual and causes gastrointestinal distress lasting up to 2 weeks in an immune-competent individual. There are few therapeutics available for eff