2,6-Diisopropylphenylboronic acid

Base Information

• Chemical Name: 2,6-Diisopropylphenylboronic acid
• CAS No.: 363166-79-4
• Molecular Formula: C12H19BO2
• Molecular Weight: 206.093
• Hs Code.: 2931900090
• Mol file: 363166-79-4.mol

Synonyms:2,6-Diisopropylphenylboronic acid;2-(3-isopropylphenyl)propylboronic acid

Chemical Property of 2,6-Diisopropylphenylboronic acid

Chemical Property:

• Melting Point: 167-172°C
• Boiling Point: 327.5±52.0 °C(Predicted)
• PKA: 8.74±0.58(Predicted)
• PSA: 40.46000
• Density: 0.99±0.1 g/cm3(Predicted)
• LogP: 1.61320
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C

Purity/Quality:

98.5% ^*data from raw suppliers

2,6-Diisopropylphenylboronic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-Diisopropylphenylboronic acid

There total 3 articles about 2,6-Diisopropylphenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

Trimethyl borate (121-43-7,63156-11-6) + 2-bromo-1,3-diisopropylbenzene (57190-17-7) → (2,6-diisopropylphenyl) boronic acid (363166-79-4)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; hexane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1039/c4dt03028a

Reference yield:

boric acid tributyl ester (688-74-4) + 2-bromo-1,3-diisopropylbenzene (57190-17-7) → (2,6-diisopropylphenyl) boronic acid (363166-79-4)

Guidance literature:

boric acid tributyl ester; 2-bromo-1,3-diisopropylbenzene; With iodine; magnesium; In tetrahydrofuran; water; at 25 - 30 ℃; for 2h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; water; at 0 ℃; for 0.5h;

Reference yield:

C14H23BO2 → (2,6-diisopropylphenyl) boronic acid (363166-79-4)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; water; at 75 ℃;

DOI:10.1021/jm8009124

upstream raw materials:

Trimethyl borate

2-bromo-1,3-diisopropylbenzene

boric acid tributyl ester

Refernces

• 1、 Ku, Hsiao-Yun,Tong, Bihai,Chi, Yun,Kao, Hao-Che,Yeh, Chia-Chi,Chang, Chih-Hao,Lee, Gene-Hsiang. "Luminescent Pt(ii) complexes bearing dual isoquinolinyl pyrazolates: Fundamentals and applications". supporting information. p. 8552 - 8563. Retrieved 2015/05/20.