364631-73-2

Basic information

• Product Name: tert-Butyl (5-forMyl-2,2-diMethyl-1,3-dioxan-5-yl)carbaMate
• Synonyms: tert-Butyl (5-forMyl-2,2-diMethyl-1,3-dioxan-5-yl)carbaMate
• CAS NO: 364631-73-2
• Molecular Formula: C₁₂H₂₁NO₅
• Molecular Weight: 259.29884
• Mol File: 364631-73-2.mol

Chemical Properties

• Melting Point: 116-119℃ (ethyl ether hexane )
• Appearance: /
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: tert-Butyl (5-forMyl-2,2-diMethyl-1,3-dioxan-5-yl)carbaMate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl (5-forMyl-2,2-diMethyl-1,3-dioxan-5-yl)carbaMate(364631-73-2)
• EPA Substance Registry System: tert-Butyl (5-forMyl-2,2-diMethyl-1,3-dioxan-5-yl)carbaMate(364631-73-2)

Safety Data

• Hazardous Substances Data: 364631-73-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
Tert-Butyl (5-formyl-2,2-dimethyl-1,3-dioxan-5-yl)carbamate is used as a key intermediate in the synthesis of various pharmaceutical drugs and bioactive compounds. Its unique structure and reactivity allow for the creation of new molecules with potential therapeutic properties.
Used in Chemical Synthesis:
Tert-Butyl (5-formyl-2,2-dimethyl-1,3-dioxan-5-yl)carbamate serves as a valuable reagent in organic chemistry reactions. Its properties enable the formation of new compounds and contribute to the advancement of scientific research in various fields.
Used in Organic Chemistry Reactions:
In the field of organic chemistry, tert-Butyl (5-formyl-2,2-dimethyl-1,3-dioxan-5-yl)carbamate is utilized as a versatile building block for the synthesis of complex organic molecules. Its unique structure allows for the development of innovative synthetic routes and the exploration of novel chemical transformations.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 77-76-9 2,2-dimethoxy-propane 
• 77-86-1 2-amino-2-hydroxymethyl-1,3-propanediol 
• 146651-71-0 N-(tert-butyloxycarbonyl)-2-amino-2-(hydroxymethyl)propane-1,3-diol 
• 53104-32-8 (5-amino-2,2-dimethyl-1,3-dioxan-5-yl)methanol 
• 364631-72-1 tert-butyl N-[5-(hydroxymethyl)-2,2-dimethyl-1,3-dioxan-5-yl]carbamate 

Downstream Products

• 946568-43-0 C₂₅H₄₁NO₆ 
• 1004539-23-4 (E)-tert-butyl (5-{4-[methoxy(methyl)carbamoyl]styryl}-2,2-dimethyl-1,3-dioxan-5-yl)carbamate 
• 946568-44-1 C₂₃H₃₃NO₆ 
• 654067-57-9 {5-[5-(4-iodo-phenyl)-1H-imidazol-2-yl]-2,2-dimethyl-[1,3]dioxan-5-yl}-carbamic acid tert-butyl ester 
• 863483-01-6 5-tert-butoxycarbonylamino-2,2-dimethyl-[1,3]dioxane-5-carboxylic acid 2-(4-iodo-phenyl)-2-oxo-ethyl ester 
• 654067-58-0 {2,2-dimethyl-5-[5-(4-octyl-phenyl)-1H-imidazol-2-yl]-[1,3]dioxan-5-yl}-carbamic acid tert-butyl ester 
• 863483-02-7 {2,2-dimethyl-5-[5-(4-oct-1-ynyl-phenyl)-1H-imidazol-2-yl]-[1,3]dioxan-5-yl}-carbamic acid tert-butyl ester 
• 364631-69-6 (1,1-bis-hydroxymethyl-prop-2-ynyl)-carbamic acid tert-butyl ester 
• 364631-75-4 [5-ethynyl-2-(4-methoxy-phenyl)-[1,3]dioxan-5-yl]-carbamic acid tert-butyl ester 
• 364631-76-5 {3-[3-azido-4,5-bis-(tert-butyl-dimethyl-silanyloxy)-6-(tert-butyl-diphenyl-silanyloxymethyl)-2-hydroxy-tetrahydro-pyran-2-yl]-1,1-bis-hydroxymethyl-prop-2-ynyl}-carbamic acid tert-butyl ester 
• 942399-89-5 (E)-{2,2-dimethyl-5-[2-(4-heptyloxy-3-trifluoromethylphenyl)vinyl]-1,3-dioxan-5-yl}carbamic acid tert-butyl ester 
• 1093172-26-9 C₂₇H₃₂F₃NO₅ 
• 1213268-19-9 methyl (E)-2-(2-(5-((tert-butoxycarbonyl)amino)-2,2-dimethyl-1,3-dioxan-5-yl)vinyl)benzoate 
• 1093173-75-1 (E)-[2,2-dimethyl-5-(2-{3-trifluoromethyl-4-[(2-trimethylsilylethoxy)methoxy]phenyl}vinyl)-1,3-dioxan-5-yl]carbamic acid t-butyl ester 

Relevant articles and documents

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The present invention relates to a composition for preventing or treating neurodegenerative diseases or depression including 2-amino-2-(1,2,3-triazol-4-yl)propane-1,3-diol derivatives as an active ingredient, and more specifically, to a pharmaceutical composition for preventing or treating neurodegenerative diseases or depression including the compound having an effect of directly inhibiting ASM activities as an active ingredient. According to the present invention, an ASM inhibiting compound of chemical formula 1 can be very useful in development of a preventive or therapeutic agent for neurodegenerative diseases including Alzheimerandprime;s disease, or a composition for diagnosing neurodegenerative diseases since the ASM inhibiting compound is directly combined with an ASM protein to obtain an excellent effect of inhibiting ASM; has treatment effects such as Aandbeta; plaque reduction, improvements in memory and anxiety, relief in neuroinflammatory diseases and the like in Alzheimerandprime;s brain environment; has a very high distribution in the brain and is very excellent in metabolic stability due to liver microsome. Further, a novel ASM inhibiting compound of chemical formula 1 can be useful used as a preventive or therapeutic agent for neurodegenerative diseases including depression as described in a conventional report that inhibition of ASM is effective in depression relief.COPYRIGHT KIPO 2020

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