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365224-13-1

3-(4-FLUOROPHENYL)-3-PIPERIDINOL is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 365224-13-1 Structure

  • Basic information

    1. Product Name: 3-(4-FLUOROPHENYL)-3-PIPERIDINOL
    2. Synonyms: 3-(4-FLUOROPHENYL)-3-PIPERIDINOL;3-(4-Fluorophenyl)-3-piperidinol HCl
    3. CAS NO:365224-13-1
    4. Molecular Formula: C11H14FNO
    5. Molecular Weight: 195.236
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 365224-13-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-(4-FLUOROPHENYL)-3-PIPERIDINOL(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-(4-FLUOROPHENYL)-3-PIPERIDINOL(365224-13-1)
    11. EPA Substance Registry System: 3-(4-FLUOROPHENYL)-3-PIPERIDINOL(365224-13-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 365224-13-1(Hazardous Substances Data)

365224-13-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 365224-13-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,6,5,2,2 and 4 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 365224-13:
(8*3)+(7*6)+(6*5)+(5*2)+(4*2)+(3*4)+(2*1)+(1*3)=131
131 % 10 = 1
So 365224-13-1 is a valid CAS Registry Number.

365224-13-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-(4-fluorophenyl)piperidin-3-ol

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:365224-13-1 SDS

365224-13-1Downstream Products

365224-13-1Relevant articles and documents

Discovery of novel non-peptide CCR1 receptor antagonists

Ng, Howard P.,Karen, May,Bauman, John G.,Ghannam, Ameen,Islam, Imadul,Liang, Meina,Horuk, Richard,Hesselgesser, Joseph,Snider, R. Michael,Perez, H. Daniel,Morrissey, Michael M.

, p. 4680 - 4694 (2007/10/03)

Ligands for the CCR1 receptor (MIP-1α and RANTES) have been implicated in a number of chronic inflammatory diseases, most notably multiple sclerosis and rheumatoid arthritis. Because these ligands share a common receptor, CCR1, we sought to discover antagonists for this receptor as an approach to treating these disorders. A novel series of 4-hydroxypiperidines has been discovered by high throughput screening (HTS) which potently inhibits the binding of MIP-1α and RANTES to the recombinant human CCR1 chemokine receptor. The structure-activity relationships of various segments of this template are described as the initial HTS lead 1 was optimized synthetically to the highly potent receptor antagonist 6s. This compound has been shown to have at least 200-fold selectivity for inhibition of CCR1 over other human 7- TM receptors, including other chemokine receptors. In addition, data obtained from in vitro functional assays demonstrate the functional antagonism of compound 6s and structurally related analogues against the CCR1 receptor in a concentration dependent manner. The discovery and optimization of potent and selective CCR1 receptor antagonists represented by compound 6s potentially represent a novel approach to the treatment of chronic inflammatory diseases.

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