365413-28-1Relevant articles and documents
Antagonists of the human A2A receptor. Part 6: Further optimization of pyrimidine-4-carboxamides
Gillespie, Roger J.,Bamford, Samantha J.,Clay, Alex,Gaur, Suneel,Haymes, Tim,Jackson, Philip S.,Jordan, Allan M.,Klenke, Burkhard,Leonardi, Stefania,Liu, Jeanette,Mansell, Howard L.,Ng, Sean,Saadi, Mona,Simmonite, Heather,Stratton, Gemma C.,Todd, Richard S.,Williamson, Douglas S.,Yule, Ian A.
experimental part, p. 6590 - 6605 (2009/12/24)
Antagonists of the human A2A receptor have been reported to have potential therapeutic benefit in the alleviation of the symptoms associated with neurodegenerative movement disorders such as Parkinson's disease. As part of our efforts to discov