The invention relates to compounds of formula 1 and to medicaments comprising these compounds, further to intermediates of formula 2 and 3.
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Page/Page column 15-16
(2008/06/13)
ISOTOPICALLY SUBSTITUTED PROTON PUMP INHIBITORS
The invention relates to benzimidazoles of Formula (1) and to pharmaceutical compositions comprising these compounds, further to intermediates of Formula (2 and 3).
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Page/Page column 17
(2008/06/13)
A process for the preparation of pantoprazole and salts thereof
A process for the preparation of pantoprazole and the salts thereof, comprising the reaction of a mercaptoimidazole with a picoline, to give a 2-pyridinyl-methylsulfinyl-2-benzimidazole intermediate, the oxidation thereof with ε-phthalimidoperhexanoic acid and the subsequent methoxylation.
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Page/Page column 5
(2010/02/11)
Process for the preparation of pantoprazole and salts thereof
A process for the preparation of pantoprazole and the salts thereof, comprising the reaction of a mercaptoimidazole with a picoline, to give a 2-pyridinyl-methylsulfinyl-2-benzimidazole intermediate, the oxidation thereof with ε-phthalimidoperhexanoic acid and the subsequent methoxylation.
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Page/Page column 3
(2010/02/11)
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