Enantioselective Phenol Coupling by Laccases in the Biosynthesis of Fungal Dimeric Naphthopyrones
Biaryl compounds are ubiquitous metabolites that are often formed by dimerization through oxidative phenol coupling. Hindered rotation around the biaryl bond can cause axial chirality. In nature, dimerizations are catalyzed by oxidative enzymes such as la
Obermaier, Sebastian,Thiele, Wiebke,Fürtges, Leon,Müller, Michael
p. 9125 - 9128
(2019/06/13)
Methods of inhibiting phosphatase activity and treatment of disorders associated therewith using naphthopyrones and derivatives thereof
The present invention relates to organic molecules capable of inhibiting protein tyrosine phosphatase activity. The invention further relates to the use of such molecules to modulate or regulate signal transduction by inhibiting protein tyrosine phosphatase activity. Finally, the invention relates to the use of such molecules to treat various disease states including diabetes mellitus.
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(2008/06/13)
Supplemental observations on atropisomerism of fungal bis(naphtho-γ-pyrone)s
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Koyama,Aida,Natori
p. 2259 - 2261
(2007/10/02)
METABOLIC PRODUCTS OF FUNGI. XXI. ON USTILAGINOIDINS. 1. THE REACTIONS
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SHIBATA,OHTA,OGIHARA
p. 1174 - 1178
(2007/10/05)
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