3705-21-3

Basic information

• Product Name: 5-HYDROXYINDOLE-3-CARBOXYLIC ACID
• Synonyms: 5-HYDROXYINDOLE-3-CARBOXYLIC ACID
• CAS NO: 3705-21-3
• Molecular Formula: C9H7NO3
• Molecular Weight: 177.16
• Product Categories: pharmacetical
• Mol File: 3705-21-3.mol

Chemical Properties

• Boiling Point: 511.4 °C at 760 mmHg
• Flash Point: 263.1 °C
• Appearance: /
• Density: 1.57 g/cm³
• Vapor Pressure: 2.79E-11mmHg at 25°C
• Refractive Index: 1.78
• Storage Temp.: 2-8°C
• PKA: 3.99±0.30(Predicted)
• CAS DataBase Reference: 5-HYDROXYINDOLE-3-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 5-HYDROXYINDOLE-3-CARBOXYLIC ACID(3705-21-3)
• EPA Substance Registry System: 5-HYDROXYINDOLE-3-CARBOXYLIC ACID(3705-21-3)

Safety Data

• Hazardous Substances Data: 3705-21-3(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
5-Hydroxyindole-3-carboxylic acid is used as a research compound for investigating its potential role in various biological functions and disease mechanisms. Its involvement in tryptophan metabolism makes it a valuable tool for studying the interplay between metabolic pathways and disease processes.
Used in Biochemical Studies:
In the field of biochemistry, 5-Hydroxyindole-3-carboxylic acid is used as a model compound to understand the structure and function of secondary metabolites. Its indole ring and carboxylic acid group provide insights into the chemical properties and interactions of such molecules within biological systems.
Used in Drug Development:
5-Hydroxyindole-3-carboxylic acid is used as a lead compound in the development of new therapeutic agents. Its potential role in disease mechanisms suggests that it could be a starting point for designing drugs that target specific metabolic pathways or biological functions.
Used in Diagnostic Applications:
5-Hydroxyindole-3-carboxylic acid is used as a biomarker in diagnostic tests to assess the levels of certain metabolites in the body. Its presence and concentration can provide information about the status of tryptophan metabolism and potentially indicate the presence of specific diseases or conditions.
Used in Nutritional Research:
In the field of nutrition, 5-Hydroxyindole-3-carboxylic acid is used as a component in studies investigating the effects of diet on metabolic pathways. Understanding its role in tryptophan metabolism can help in developing dietary interventions for various health conditions.

InChI:InChI=1/C9H7NO3/c11-5-1-2-8-6(3-5)7(4-10-8)9(12)13/h1-4,10-11H,(H,12,13)

Upstream product

• 24370-73-8 5-benzyloxyindole-3-carboxylic acid 
• 10406-06-1 5-bromo-1H-indole-3-carboxylic acid 
• 1215-59-4 5-benzyloxy-1H-indole 

Relevant articles and documents

Biocatalytic Cross-Coupling of Aryl Halides with a Genetically Engineered Photosensitizer Artificial Dehalogenase

Devising artificial photoenzymes for abiological bond-forming reactions is of high synthetic value but also a tremendous challenge. Disclosed herein is the first photobiocatalytic cross-coupling of aryl halides enabled by a designer artificial dehalogenase, which features a genetically encoded benzophenone chromophore and site-specifically modified synthetic NiII(bpy) cofactor with tunable proximity to streamline the dual catalysis. Transient absorption studies suggest the likelihood of energy transfer activation in the elementary organometallic event. This design strategy is viable to significantly expand the catalytic repertoire of artificial photoenzymes for useful organic transformations.