- Preparing method for 5-iodine-1, 2, 3-benzenetricarboxylic acid
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The invention relates to a preparing method for an organic iodine substituted compound, in particular to a preparing method for 5-iodine-1, 2, 3-benzenetricarboxylic acid. The preparing method includes the steps that firstly a reaction is performed when p
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Paragraph 0024
(2017/05/26)
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- INTERACTION OF 5-AZIDO-1,2,3-BENZENETRICARBOXYLIC ACID WITH THE MITOCHONDRIAL TRICARBOXYLATE CARRIER
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5-azido-1,2,3-benzenetricarboxylic acid (5-N3-BTA), a new derivative of 1,2,3-benzenetricarboxylic acid (BTA) has been synthesised in satisfactory overall yields (25percent).This azido compound inhibits the transport of citrate either in mitochondria or in reconstituted partially purified tricarboxylate carrier, both in the dark and upon irradiation.However, the inhibition is nearly completely supressed after washing the mitochondria, indicating that upon irradiation 5-N3-BTA does not form a covalent bond with the citrate-binding site of the tricarboxylate transport system.
- Capassso, Renato,Randazzo, Giacomino,Stipani, Italo,Zara, Vincenzo,Palmieri, Ferdinando
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p. 449 - 452
(2007/10/02)
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