375369-29-2 Usage
Uses
Used in Chemical Synthesis:
2,4,5-Trifluoromandelic acid is used as a building block for the synthesis of other organic compounds. Its unique structure and reactivity make it a valuable intermediate in the production of various chemical products.
Used in Pharmaceutical Industry:
2,4,5-Trifluoromandelic acid is used as a chiral resolving agent in chromatographic separation processes. This application is crucial for the purification and isolation of enantiomers, which are essential in the development of single-enantiomer drugs to improve efficacy and reduce side effects.
Used in Drug Development:
Due to its unique chemical properties, 2,4,5-Trifluoromandelic acid has potential applications in the development of new drugs and pharmaceuticals. Its ability to interact with biological targets and influence biochemical pathways makes it a promising candidate for the creation of novel therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 375369-29-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,7,5,3,6 and 9 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 375369-29:
(8*3)+(7*7)+(6*5)+(5*3)+(4*6)+(3*9)+(2*2)+(1*9)=182
182 % 10 = 2
So 375369-29-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H5F3O3/c9-4-2-6(11)5(10)1-3(4)7(12)8(13)14/h1-2,7,12H,(H,13,14)
375369-29-2Relevant articles and documents
EFFICIENT PROCESS FOR THE PREPARATION OF SITAGLIPTIN THROUGH A VERY EFFECTIVE PREPARATION OF THE INTERMEDIATE 2,4,5-TRIFLUOROPHENYLACETIC ACID
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Paragraph 00159; 00160, (2019/01/21)
Object of the present invention is an efficient process for the preparation of the active pharmaceutical ingredient Sitagliptine and the 2,4,5-trifluorophenylacetic acid (TFAA) and salt thereof, which is a key intermediate for the synthesis of Sitagliptine.
PROCESS FOR THE PREPARATION OF FLUOROPHENYLACETIC ACIDS AND DERIVATIVES THEREOF
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Page/Page column 13-14, (2008/12/06)
The object of the present invention is a process for the preparation of fluorophenylacetic acids and derivatives thereof, particularly of 2,4, 5-trifluorophenylacetic acid, starting from the corresponding mandelic acids.
