- Synthesis and pharmacological activity of alkaloids from embryo of lotus, Nelumbo nucifera
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Bisbenzylisoquinoline alkaloid, nelumboferine which was recently isolated from the embryo of Nelumbo nucifera, and stereoisomers of neferine, which is a major alkaloid of the embryo of N. nucifera, were stereoselectively synthesized. Pharmacological activity of nelumboferine, stereoisomers of neferine, liensinine, isoliensinine, and O-methylneferine were evaluated.
- Nishimura, Katsumi,Horii, Shinji,Tanahashi, Takao,Sugimoto, Yumi,Yamada, Jun
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