New method of synthesis and biological evaluation of some combretastatin A-4 analogues
A series of novel combretastatin A-4 analogues was synthesized in 36-64% yields by Negishi cross-coupling reaction under mild conditions. The prepared compounds exhibit good cytotoxicity against HBL100 epithelial cell lines (IC50=0.022-10.31 ). Georg Thieme Verlag Stuttgart · New York.
Malysheva, Yulia B.,Combes, Sebastien,Fedorov, Alexey Yu.,Knochel, Paul,Gavryushin, Andrei E.
supporting information; experimental part
p. 1205 - 1208
(2012/06/29)
More Articles about upstream products of 3824-21-3
