38275-04-6

Basic information

• Product Name: 2,6-OCTANEDIONE
• Synonyms: 2,6-OCTANEDIONE
• CAS NO: 38275-04-6
• Molecular Formula: C₈H₁₄O₂
• Molecular Weight: 142.2
• Mol File: 38275-04-6.mol

Chemical Properties

• Boiling Point: 231.2 °C at 760 mmHg
• Flash Point: 84.1 °C
• Appearance: /
• Density: 0.918 g/cm³
• Vapor Pressure: 0.063mmHg at 25°C
• Refractive Index: 1.419
• CAS DataBase Reference: 2,6-OCTANEDIONE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-OCTANEDIONE(38275-04-6)
• EPA Substance Registry System: 2,6-OCTANEDIONE(38275-04-6)

Safety Data

• Hazardous Substances Data: 38275-04-6(Hazardous Substances Data)

Usage

Synthesis Reference(s)

Journal of the American Chemical Society, 103, p. 206, 1981 DOI: 10.1021/ja00391a046

InChI:InChI=1/C8H14O2/c1-3-8(10)6-4-5-7(2)9/h3-6H2,1-2H3

Upstream product

• 1122-69-6 2-ethyl-6-methylpyridine 
• 1123-32-6 endo-5,7-Dimethyl-6,8-dioxabicyclo<3.2.1>octane 
• 24395-06-0 CH₃COCH₂CH₂CH₂CCMe 
• 19780-56-4 1-methyl-2-ethylcyclopentene 
• 76745-37-4 1,5-dimethyl-6,7-dioxabicyclo<3.2.1.>octane 
• 78-94-4 methyl vinyl ketone 
• 78-93-3 butanone 
• 111-13-7 hexyl-methyl-ketone 

Downstream Products

• 1122-20-9 2,3-dimethylcyclohex-2-en-1-one 
• 17299-34-2 3-ethylcyclohex-2-en-1-one 

Relevant articles and documents

REMOTE OXIDATION OF KETONES TO γ- AND δ-DIKETONES

A single stage remote oxidation of ketones to γ- and δ-diketones has been carried out in a sodium peroxysulfate-iron(II) sulfate system.

A New Method for the Preparation of 1,5-Dicarbonyl Compounds from Bicyclic Ketals

1,5-Dicarbonyl compounds have been prepared from bicyclic ketals in high yield under mild conditions by using aluminium chloride-sodium iodide in methylene dichloride.

REGIOSELECTIVE HYDRATION OF ALKYNONES BY PALLADIUM CATALYSIS

Diketones are regioselectively prepared from alkynyl ketones under mild conditions by palladium catalysis; 5-heptyn-2-one and 2-(2-nonynyl)cyclohexanone give 1,4-diketones whereas 2-(2-heptynyl)cyclopentanone and 5,6-didehydroprostaglandin E2 methyl ester afford 1,5-diketones.

A CONVENIENT PROCEDURE FOR CARBOXYLATION-ROBINSON ANNULATIONS OF KETONES USING TRIETHYLAMINE BASE IN THE PRESENCE OF MAGNESIUM CHLORIDE

Carboxylation of ketones with carbon dioxide in the presence of magnesium chloride and triethylamine followed by reaction with methyl vinyl ketone gives satisfactory yields of Michael and Robinson annulation products.

THE PREPARATION OF 1,4-DICARBONYL COMPOUNDS BY PHOTOREACTION OF KETONES IN THE PRESENCE OF OXIDANTS

Phenyl alkyl ketones were photo-irradiated in the presence of Cr(VI) or Mn(VII) oxidants to yield 1,4-dicarbonyl compounds regiospecifically while 2-octanone gave a regioisomeric mixture of 2,5-, 2,6-, and 2,7-octadiones.