The invention relates to a preparation method of aliphatic carboxylic acid amide. The method comprises the following step: carrying out a reaction on aliphatic carboxylic acid and monoalkylamine or dialkylamine with 1-4 carbon atoms in the presence of ceric oxide. By using the method, aliphatic carboxylic acid amide can be prepared with high yield, and a catalyst shows an excellent catalytic efficiency and reusing stability.
-
Paragraph 0065; 0066; 0086; 0087
(2017/01/09)
A METHOD OF TREATING PERIPHERAL INFLAMMATORY DISEASE
An active for use in the treatment or inhibition of an inflammatory disease associated with over-activation of Toll-like Receptor 4 (TLR4), Toll-like Receptor 2 (TLR2) and Myeloid differentiating protein 88 (Myd88) adaptor-like protein (Mal) while maintaining a subject's ability to respond normally to a pathogen, in which the active is an oleamide or a derivative thereof.
-
Paragraph 0078-0084; 0137-0128
(2016/12/01)
PROCESS FOR PRODUCING ALIPHATIC CARBOXYLIC ACID AMIDE
The present invention relates to a process for producing an aliphatic carboxylic acid amide, including the step of reacting an aliphatic carboxylic acid or an alkyl ester thereof containing an alkyl group having 1 to 4 carbon atoms with a mono- or dialkylamine containing an alkyl group or groups having 1 to 4 carbon atoms in the presence of a solid acid catalyst containing titanium oxide as a main component and an oxide or oxides of at least one element selected from elements (except titanium) belonging to Groups 4, 5 and 14 of the long form of the periodic table, wherein the catalyst has an average particle diameter of 2 μm or more. The process for producing an aliphatic carboxylic acid amide according to the present invention has a high reaction efficiency of the reaction of the aliphatic carboxylic acid or alkyl ester thereof with the mono- or dialkylamine, and shows an excellent filtration efficiency in separation of the catalyst.
-
Page/Page column 5
(2010/12/29)
One pot direct synthesis of amides or oxazolines from carboxylic acids using Deoxo-Fluor reagent
A mild and highly efficient one pot-one step condensation and/or condensation-cyclization of various acids to amides and/or oxazolines using Deoxo-Fluor reagents is described. Parallel syntheses of various free fatty acids with 2-amino-2,2-dimethyl-1-propanol resulted with excellent yields.
Kangani, Cyrous O.,Kelley, David E.
p. 8917 - 8920
(2007/10/03)
A CONVENIENT METHOD FOR THE SYNTHESIS OF CARBOXAMIDES AND PEPTIDES BY THE USE OF TETRABUTYLAMMONIUM SALTS
Various carboxamides and peptides are prepared in good yields by treatment of free acids and amines in H2O-dichloromethane or aqueous THF with bis(o-nitrophenyl) phenylphosphonate in the presence of tetrabutylammonium hydrogen sulfate or bromide.Carboxylic esters are also successfully converted to amides via carboxylate salts in one-pot.
Watanabe, Yutaka,Mukaiyama, Teruaki
p. 285 - 288
(2007/10/02)
More Articles about upstream products of 3886-90-6