3886-90-6

Usage

Uses

Used in Lubricant Applications:
Oleamide is utilized as a lubricant in various industries due to its ability to reduce friction and wear between surfaces. Its properties make it suitable for use in mechanical components and systems where smooth operation and reduced energy consumption are desired.
Used in Anti-static Agent Applications:
As an anti-static agent, oleamide helps to dissipate static charges that can build up on surfaces, reducing the risk of electrical discharge and damage to sensitive equipment or materials.
Used in Slip Additive Applications:
Oleamide is employed as a slip additive in the manufacturing of plastics and films, enhancing their smoothness and reducing the coefficient of friction. This improves the processability and performance of these materials in various applications.
Used in Pharmaceutical and Nutraceutical Applications:
Oleamide is being studied for its potential use in the treatment of substance abuse and addiction, as well as for its neuroprotective properties. Its antioxidant and anti-inflammatory effects also make it a compound of interest in the development of new pharmaceutical and nutraceutical products.
Used in Sleep Regulation Applications:
Oleamide's role in sleep regulation makes it a potential candidate for the development of sleep aids and treatments for sleep disorders, contributing to improved sleep quality and overall health.
Used in Antioxidant and Anti-inflammatory Applications:
The antioxidant and anti-inflammatory properties of oleamide make it a valuable compound for the development of products aimed at reducing oxidative stress and inflammation, which can contribute to various health conditions and diseases.

InChI:InChI=1/C20H41NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20(22)21(2)3/h4-19H2,1-3H3

Upstream product

• 124-40-3 dimethyl amine 
• 112-76-5 Stearoyl chloride 
• 111-61-5 stearic acid ethyl ester 
• 506-59-2 N,N-dimethylammonium chloride 
• 57-11-4 stearic acid 
• 143-07-7 lauric acid 

Downstream Products

• 124-28-7 N,N-dimethyl-n-octadecylamine 
• 112-92-5 1-octadecanol 
• 4088-22-6 N-methyldioctadecylamine 
• 161560-92-5 benzyl (2,3,5-trimethyl-4-octadecanoylpyrrol-1-yl)acetate 
• 638-66-4 n-Octadecanal 

Relevant academic research and scientific papers

Aliphatic carboxylic acid amide preparation method

The invention relates to a preparation method of aliphatic carboxylic acid amide. The method comprises the following step: carrying out a reaction on aliphatic carboxylic acid and monoalkylamine or dialkylamine with 1-4 carbon atoms in the presence of ceric oxide. By using the method, aliphatic carboxylic acid amide can be prepared with high yield, and a catalyst shows an excellent catalytic efficiency and reusing stability.

A METHOD OF TREATING PERIPHERAL INFLAMMATORY DISEASE

An active for use in the treatment or inhibition of an inflammatory disease associated with over-activation of Toll-like Receptor 4 (TLR4), Toll-like Receptor 2 (TLR2) and Myeloid differentiating protein 88 (Myd88) adaptor-like protein (Mal) while maintaining a subject's ability to respond normally to a pathogen, in which the active is an oleamide or a derivative thereof.

PROCESS FOR PRODUCING ALIPHATIC CARBOXYLIC ACID AMIDE

The present invention relates to a process for producing an aliphatic carboxylic acid amide, including the step of reacting an aliphatic carboxylic acid or an alkyl ester thereof containing an alkyl group having 1 to 4 carbon atoms with a mono- or dialkylamine containing an alkyl group or groups having 1 to 4 carbon atoms in the presence of a solid acid catalyst containing titanium oxide as a main component and an oxide or oxides of at least one element selected from elements (except titanium) belonging to Groups 4, 5 and 14 of the long form of the periodic table, wherein the catalyst has an average particle diameter of 2 μm or more. The process for producing an aliphatic carboxylic acid amide according to the present invention has a high reaction efficiency of the reaction of the aliphatic carboxylic acid or alkyl ester thereof with the mono- or dialkylamine, and shows an excellent filtration efficiency in separation of the catalyst.

One pot direct synthesis of amides or oxazolines from carboxylic acids using Deoxo-Fluor reagent

A mild and highly efficient one pot-one step condensation and/or condensation-cyclization of various acids to amides and/or oxazolines using Deoxo-Fluor reagents is described. Parallel syntheses of various free fatty acids with 2-amino-2,2-dimethyl-1-propanol resulted with excellent yields.

A CONVENIENT METHOD FOR THE SYNTHESIS OF CARBOXAMIDES AND PEPTIDES BY THE USE OF TETRABUTYLAMMONIUM SALTS

Various carboxamides and peptides are prepared in good yields by treatment of free acids and amines in H2O-dichloromethane or aqueous THF with bis(o-nitrophenyl) phenylphosphonate in the presence of tetrabutylammonium hydrogen sulfate or bromide.Carboxylic esters are also successfully converted to amides via carboxylate salts in one-pot.