39050-13-0 Usage
Uses
Used in Pharmaceutical Industry:
5-(2-Aminoethyl)-1H-imidazol-2-amine is used as a target for antihistamine drugs for the treatment of allergy symptoms and other histamine-related conditions. Antihistamines block the effects of histamine, providing relief from symptoms such as itching, sneezing, and watery eyes.
Used in Research and Development:
5-(2-Aminoethyl)-1H-imidazol-2-amine is used as a research compound in the study of histamine's role in various physiological processes, including neurotransmission, inflammation, and allergic reactions. This research helps in the development of new drugs and therapies targeting histamine pathways.
Used in Diagnostics:
5-(2-Aminoethyl)-1H-imidazol-2-amine is used as a diagnostic marker in certain medical tests to assess the presence or activity of histamine in the body. Elevated levels of histamine may indicate an allergic reaction or other histamine-related conditions.
Used in Food Industry:
5-(2-Aminoethyl)-1H-imidazol-2-amine is used as a flavor enhancer and preservative in the food industry. It is responsible for the umami taste and can help to extend the shelf life of certain food products.
Used in Cosmetics Industry:
5-(2-Aminoethyl)-1H-imidazol-2-amine is used in some cosmetic products as a skin soothing and anti-inflammatory agent. It can help to reduce redness, itching, and irritation caused by allergies or other skin conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 39050-13-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,0,5 and 0 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 39050-13:
(7*3)+(6*9)+(5*0)+(4*5)+(3*0)+(2*1)+(1*3)=100
100 % 10 = 0
So 39050-13-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H10N4/c6-2-1-4-3-8-5(7)9-4/h3H,1-2,6H2,(H3,7,8,9)
39050-13-0Relevant articles and documents
AMINO-HETEROARYL-CONTAINING PROKINETICIN 1 RECEPTOR ANTAGONISTS
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Page/Page column 53, (2009/06/27)
The present invention relates to certain novel compounds of Formula (I): and methods for preparing these compounds, compositions, intermediates and derivatives thereof and for the treatment of prokineticin 1 or prokinetin 1 receptor mediated disorders.
Design, synthesis, and biological evaluation of pyrazinones containing novel P1 needles as inhibitors of TF/VIIa
Trujillo, John I.,Huang, Horng-Chih,Neumann, William L.,Mahoney, Matthew W.,Long, Scott,Huang, Wei,Garland, Danny J.,Kusturin, Carrie,Abbas, Zaheer,South, Michael S.,Reitz, David B.
, p. 4568 - 4574 (2008/02/11)
Herein is described the design, synthesis, and enzymatic activity of a series of substituted pyrazinones as inhibitors of the TF/VIIa complex. These inhibitors were designed to explore replacement and variation of the P1 amidine described previously [J. Med. Chem. 2003, 46, 4050]. The P1 needle replacements were selected based upon their reduced basicity compared to the parent phenyl amidine (pKa ～ 12). A contributing factor towards the oral bioavailability of a compound is the ionization state of the compound in the intestinal tract. The desired outcome of the study was to identify an orally bioavailable TF-VIIa inhibitor.
Imidazole H-2 agonists. Synthesis and activity of 2-(2-amino-4-imidazolyl)ethylamine (2-aminohistamine) dihydrochloride
Vitali,Impicciatore,Plazzi,Bordi,Vitto
, p. 70 - 80 (2007/10/02)
The syntheses of 2-(2-amino-4-imidazolyl)ethylamine (2-aminohistamine) dihydrochloride and of the corresponding 5-methyl derivative are described. The histamine-like properties of the two salts are tested in vitro on isolated ileum and gastric fundus of guinea-pig. The results are discussed and compared with those of other H2-agonists.
