393078-38-1Relevant articles and documents
Synthesis of new C2-symmetric chiral bisamides from (1S,2S)-cyclohexane-1,2-dicarboxylic acid
Zhou, Chan,Xu, Jiaxi
, p. 1396 - 1405 (2015/01/09)
series of new C2-symmetric (1S,2S)-cyclohexane-1,2-dicarboxamides was synthesized from (1S,2S)-cyclohexane-1,2-dicarbonyl dichloride and N-benzyl-substituted aromatic amines, which were prepared from 2-aminopyridine, 2-chloroaniline, and 2-aminophenol via imine formation with benzaldehyde and subsequent reduction with NaBH4. (1S,2S)-N,N'-Dibenzyl-N,N'-bis[2-(benzyloxy)-phenyl]cyclohexane-1,2-dicarboxamide was converted to (1S,2S)-N,N'-dibenzyl-N,N'-bis(2-hydroxyphenyl) cyclohexane-1,2-dicarboxamide via hydrogenolysis in the presence of Pd(OH)2 on active carbon powder.
Synthesis of New C2-Symmetric Chiral Bisamides from (1S,2S)-Cyclohexane-1,2-dicarboxylic Acid
Zhou, Chan,Xu, Jiaxi
, p. 1396 - 1405 (2015/08/25)
A series of new C2-symmetric (1S,2S)-cyclohexane-1,2-dicarboxamides was synthesized from (1S,2S)-cyclohexane-1,2-dicarbonyl dichloride and N-benzyl-substituted aromatic amines, which were prepared from 2-aminopyridine, 2-chloroaniline, and 2-aminophenol via imine formation with benzaldehyde and subsequent reduction with NaBH4. (1S,2S)-N,N′-Dibenzyl-N,N′-bis[2-(benzyloxy)phenyl]cyclohexane-1,2-dicarboxamide was converted to (1S,2S)-N,N′-dibenzyl-N,N′-bis(2-hydroxyphenyl)cyclohexane-1,2-dicarboxamide via hydrogenolysis in the presence of Pd(OH)2 on active carbon powder.
