39539-68-9Relevant articles and documents
2-Phenylimidazo[1,2-b]pyridazine derivatives highly active against Haemonchus contortus
Ali, Abdelselam,Cablewski, Teresa,Francis, Craig L.,Ganguly, Ashit K.,Sargent, Roger M.,Sawutz, David G.,Winzenberg, Kevin N.
scheme or table, p. 4160 - 4163 (2011/08/10)
A series of 2-phenylimidazo[1,2-b]pyridazine derivatives were synthesized and evaluated for their in vitro anthelmintic activity against Haemonchus contortus. The most active compounds had in vitro LD99 values of 30 nM, which is comparable to that of the benchmark commercial nematocide, Ivermectin.
Design, synthesis, and bioactivity study of novel benzoylpyridazyl ureas
Ranfeng,Zhang, Yonglin,Fuchun,Wang, Qingmin
experimental part, p. 6356 - 6361 (2010/07/05)
A series of novel benzoylpyridazyl ureas were designed and synthesized from maleic anhydride and hydrazine monohydrate. These benzoylureas were identified by 1H NMR spectroscopy and element analysis. The bioactivities of the new compounds were evaluated. These compounds exhibited larvicidal activities against oriental armyworm, and in particular, compound 13 displayed comparable activity to the commercial insecticide Hexaflumuron. Most of these compounds also had some larvicidal activities against mosquito. Interestingly, some compounds showed good plant growth regulatory activities.
A revision of the alcoholysis and alkanethiolysis of 3-amino-6-chloropyridazine
Maes,Lemiere,Dommisse,Haemers
, p. 1215 - 1218 (2007/10/03)
The synthesis of 3-amino-6-alkoxy- and 3-amino-6-alkylthiopyridazines via nucleophilic aromatic substitution on 3-amino-6-chloropyridazine is described. In contrast to literature reports, no pressure tube is required to perform these reactions.
