Welcome to LookChem.com Sign In|Join Free

CAS

  • or

141-52-6 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 141-52-6 Structure
  • Basic information

    1. Product Name: Sodium ethoxide
    2. Synonyms: Sodium ethoxide 95%;Sodium ethoxide 96%;Sodium ethoxide solution;sodium ethylate solution;Sodiumethoxideinethanol;SODIUM ETHYLATE SOLUTION, ~21% IN ETHYL ALCOHOL, DENAT.;SODIUM ETHOXIDE, 21 WT. % SOLUTION IN DE NATURED ETHYL ALCOHOL;Sodium ethoxide, 21% in ethanol
    3. CAS NO:141-52-6
    4. Molecular Formula: C2H5NaO
    5. Molecular Weight: 68.05
    6. EINECS: 205-487-5
    7. Product Categories: Classes of Metal Compounds;Na (Sodium) Compounds (excluding simple sodium salts);Typical Metal Compounds;metal alkoxide;Organics
    8. Mol File: 141-52-6.mol
    9. Article Data: 311
  • Chemical Properties

    1. Melting Point: 260 °C
    2. Boiling Point: 91°C
    3. Flash Point: 48 °F
    4. Appearance: Yellow to brown/Liquid
    5. Density: 0.868 g/mL at 25 °C
    6. Vapor Density: 1.6 (vs air)
    7. Vapor Pressure: <0.1 mm Hg ( 20 °C)
    8. Refractive Index: n20/D 1.386
    9. Storage Temp.: Store at R.T.
    10. Solubility: Soluble in ethanol and methanol.
    11. Water Solubility: Miscible
    12. Sensitive: Moisture Sensitive
    13. Stability: Reacts violently with acids, water. Incompatible with chlorinated solvents, moisture. Absorbs carbon dioxide from the air. Highl
    14. Merck: 14,8539
    15. BRN: 3593646
    16. CAS DataBase Reference: Sodium ethoxide(CAS DataBase Reference)
    17. NIST Chemistry Reference: Sodium ethoxide(141-52-6)
    18. EPA Substance Registry System: Sodium ethoxide(141-52-6)
  • Safety Data

    1. Hazard Codes: F,C,Xi,N
    2. Statements: 11-14-34-36/37/38-68/20/21/22-51/53-20/21/22
    3. Safety Statements: 8-16-26-43-45-36/37/39-36-61
    4. RIDADR: UN 3274 3/PG 2
    5. WGK Germany: 1
    6. RTECS:
    7. F: 3-8-10-23
    8. TSCA: Yes
    9. HazardClass: 4.2
    10. PackingGroup: II
    11. Hazardous Substances Data: 141-52-6(Hazardous Substances Data)

141-52-6 Usage

Chemical Description

Sodium ethoxide is a white crystalline solid that is used as a strong base and as a reagent in organic synthesis.

Chemical Description

Sodium ethoxide, for example, is a strong base that can deprotonate acidic compounds, while dimethyl sulfoxide is a polar aprotic solvent that can dissolve a wide range of organic and inorganic compounds.

Chemical Description

Sodium ethoxide is a strong base and a reagent used in organic synthesis, while piperidine is a heterocyclic organic compound used as a solvent and a base.

Check Digit Verification of cas no

The CAS Registry Mumber 141-52-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,4 and 1 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 141-52:
(5*1)+(4*4)+(3*1)+(2*5)+(1*2)=36
36 % 10 = 6
So 141-52-6 is a valid CAS Registry Number.
InChI:InChI=1/C2H6O.Na/c1-2-3;/h3H,2H2,1H3;/q;+1

141-52-6 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Alfa Aesar

  • (45590)  Sodium ethoxide, 21% w/w soln. in ethanol, packaged under Argon in resealable ChemSeal? bottles   

  • 141-52-6

  • 100ml

  • 148.0CNY

  • Detail
  • Alfa Aesar

  • (45590)  Sodium ethoxide, 21% w/w soln. in ethanol, packaged under Argon in resealable ChemSeal? bottles   

  • 141-52-6

  • 500ml

  • 320.0CNY

  • Detail
  • Alfa Aesar

  • (L13083)  Sodium ethoxide, 21% w/w in ethanol   

  • 141-52-6

  • 100ml

  • 248.0CNY

  • Detail
  • Alfa Aesar

  • (L13083)  Sodium ethoxide, 21% w/w in ethanol   

  • 141-52-6

  • 500ml

  • 562.0CNY

  • Detail
  • Alfa Aesar

  • (L13083)  Sodium ethoxide, 21% w/w in ethanol   

  • 141-52-6

  • 2500ml

  • 2039.0CNY

  • Detail
  • Alfa Aesar

  • (L06230)  Sodium ethoxide, 96%   

  • 141-52-6

  • 100g

  • 360.0CNY

  • Detail
  • Alfa Aesar

  • (L06230)  Sodium ethoxide, 96%   

  • 141-52-6

  • 500g

  • 580.0CNY

  • Detail
  • Alfa Aesar

  • (L06230)  Sodium ethoxide, 96%   

  • 141-52-6

  • 2000g

  • 1122.0CNY

  • Detail
  • Sigma-Aldrich

  • (71210)  Sodiumethoxide  technical, ≥95% (T)

  • 141-52-6

  • 71210-50G

  • 510.12CNY

  • Detail
  • Sigma-Aldrich

  • (71210)  Sodiumethoxide  technical, ≥95% (T)

  • 141-52-6

  • 71210-250G

  • 785.07CNY

  • Detail
  • Sigma-Aldrich

  • (156248)  Sodiumethoxide  95%

  • 141-52-6

  • 156248-5G

  • 427.05CNY

  • Detail
  • Sigma-Aldrich

  • (156248)  Sodiumethoxide  95%

  • 141-52-6

  • 156248-100G

  • 718.38CNY

  • Detail

141-52-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name sodium ethoxide

1.2 Other means of identification

Product number -
Other names Sodium Ethylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:141-52-6 SDS

141-52-6Synthetic route

ethanol
64-17-5

ethanol

sodium ethanolate
141-52-6

sodium ethanolate

Conditions
ConditionsYield
With sodium at 25 - 30℃; under 75.0075 Torr; for 2h; Pressure; Temperature; Large scale;97.62%
With sodium iodide at 28℃; Mechanism; Rate constant; Irradiation; investigated by a time-of-flight mass spectrometer;
at 200℃; Leiten in eine Suspension von NaOH in Paraffinoel;
phenythoin
57-41-0

phenythoin

ethyl bromoacetate
105-36-2

ethyl bromoacetate

A

ethyl 2-(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)acetate
976-85-2

ethyl 2-(2,5-dioxo-4,4-diphenylimidazolidin-1-yl)acetate

B

sodium ethanolate
141-52-6

sodium ethanolate

Conditions
ConditionsYield
In ethanolA 96%
B n/a
oxalic acid diethyl ester
95-92-1

oxalic acid diethyl ester

A

spiro [4H-1-benzopyran-4,2'-pyrrolidine]3'-carboxylic acid

spiro [4H-1-benzopyran-4,2'-pyrrolidine]3'-carboxylic acid

B

sodium ethanolate
141-52-6

sodium ethanolate

Conditions
ConditionsYield
With sodium In ethanolA 84%
B n/a
3-cyclohexene-1-chloromethane

3-cyclohexene-1-chloromethane

diethyl malonate
105-53-3

diethyl malonate

sodium ethanolate
141-52-6

sodium ethanolate

Conditions
ConditionsYield
In diethyl ether; ethanol; water48%
diethyl ether
60-29-7

diethyl ether

isopentyl sodium
2875-34-5

isopentyl sodium

sodium ethanolate
141-52-6

sodium ethanolate

diethyl ether
60-29-7

diethyl ether

ethyl sodium
676-54-0

ethyl sodium

A

ethane
74-84-0

ethane

B

ethene
74-85-1

ethene

C

sodium ethanolate
141-52-6

sodium ethanolate

diethyl ether
60-29-7

diethyl ether

ethyl sodium
676-54-0

ethyl sodium

sodium ethanolate
141-52-6

sodium ethanolate

pentaethoxyethane
58995-69-0

pentaethoxyethane

ethyl sodium
676-54-0

ethyl sodium

A

ethane
74-84-0

ethane

B

tetraethoxyethene
40923-93-1

tetraethoxyethene

C

sodium ethanolate
141-52-6

sodium ethanolate

(+/-)-erythro-5-oxo-2.3.5-triphenyl-valeric acid ethyl ester
62071-28-7

(+/-)-erythro-5-oxo-2.3.5-triphenyl-valeric acid ethyl ester

1,3-diphenyl-propen-3-one
614-47-1

1,3-diphenyl-propen-3-one

benzene
71-43-2

benzene

A

3-benzoyl-1,2,4,6-tetraphenyl-cyclohex-3-enecarboxylic acid ethyl ester
859176-77-5

3-benzoyl-1,2,4,6-tetraphenyl-cyclohex-3-enecarboxylic acid ethyl ester

B

sodium ethanolate
141-52-6

sodium ethanolate

C10H12N3O8(1-)

C10H12N3O8(1-)

A

2,4,6-trinitro-phenetole
4732-14-3

2,4,6-trinitro-phenetole

B

sodium ethanolate
141-52-6

sodium ethanolate

Conditions
ConditionsYield
In ethanol at 25℃; Equilibrium constant; measured by UV spectroscopy;
C9H10N3O8(1-)

C9H10N3O8(1-)

A

sodium ethanolate
141-52-6

sodium ethanolate

B

1-methoxy-2,4,6-trinitrobenzene
606-35-9

1-methoxy-2,4,6-trinitrobenzene

Conditions
ConditionsYield
In ethanol at 25℃; Equilibrium constant; measured by UV spectroscopy;
C11H14N3O8(1-)

C11H14N3O8(1-)

A

n-propyl-2,4,6-trinitrophenyl ether
10242-24-7

n-propyl-2,4,6-trinitrophenyl ether

B

sodium ethanolate
141-52-6

sodium ethanolate

Conditions
ConditionsYield
In ethanol at 25℃; Equilibrium constant; measured by UV spectroscopy;
C11H14N3O8(1-)

C11H14N3O8(1-)

A

2,4,6-trinitrophenyl isopropyl ether
10242-23-6

2,4,6-trinitrophenyl isopropyl ether

B

sodium ethanolate
141-52-6

sodium ethanolate

Conditions
ConditionsYield
In ethanol at 25℃; Equilibrium constant; measured by UV spectroscopy;
C16H11N6O13(1-)

C16H11N6O13(1-)

A

2,2',4.4',6,6'-hexanitrostilbene
19138-90-0

2,2',4.4',6,6'-hexanitrostilbene

B

sodium ethanolate
141-52-6

sodium ethanolate

Conditions
ConditionsYield
In ethanol; dimethyl sulfoxide at 25℃; Rate constant; Equilibrium constant; sodium perchlorate;
C16H11N6O13(1-)

C16H11N6O13(1-)

A

2,2',4.4',6,6'-hexanitrostilbene
19138-90-0

2,2',4.4',6,6'-hexanitrostilbene

B

sodium ethanolate
141-52-6

sodium ethanolate

Conditions
ConditionsYield
In ethanol; dimethyl sulfoxide at 25℃; Rate constant; Equilibrium constant;
C18H16N6O14(2-)

C18H16N6O14(2-)

A

2,2',4.4',6,6'-hexanitrostilbene
19138-90-0

2,2',4.4',6,6'-hexanitrostilbene

B

sodium ethanolate
141-52-6

sodium ethanolate

Conditions
ConditionsYield
In ethanol; dimethyl sulfoxide at 25℃; Rate constant; Equilibrium constant; sodium perchlorate;
2-phenylmethylsulfonylpyridine-1-oxide
14694-58-7

2-phenylmethylsulfonylpyridine-1-oxide

sodium ethanolate
141-52-6

sodium ethanolate

A

2-ethoxylpyridine N-oxide
3445-09-8

2-ethoxylpyridine N-oxide

B

C7H7O2S(1-)*Na(1+)

C7H7O2S(1-)*Na(1+)

Conditions
ConditionsYield
In ethanol for 0.25h; Heating;A n/a
B 100%
2-(Propane-2-sulfonyl)-pyridine 1-oxide
62381-86-6

2-(Propane-2-sulfonyl)-pyridine 1-oxide

sodium ethanolate
141-52-6

sodium ethanolate

A

2-ethoxylpyridine N-oxide
3445-09-8

2-ethoxylpyridine N-oxide

B

C3H7O2S(1-)*Na(1+)

C3H7O2S(1-)*Na(1+)

Conditions
ConditionsYield
In ethanol for 0.25h; Heating;A n/a
B 100%
N-benzoyl-L-glutamic acid α-methyl ester
124126-80-3

N-benzoyl-L-glutamic acid α-methyl ester

sodium ethanolate
141-52-6

sodium ethanolate

N-benzoyl-L-glutamic acid α-ethyl ester
23262-03-5

N-benzoyl-L-glutamic acid α-ethyl ester

Conditions
ConditionsYield
In ethanol for 1.5h; Ambient temperature;100%
sodium ethanolate
141-52-6

sodium ethanolate

2-Methanesulfonyl-pyridine 1-oxide
75853-86-0

2-Methanesulfonyl-pyridine 1-oxide

A

2-ethoxylpyridine N-oxide
3445-09-8

2-ethoxylpyridine N-oxide

B

CH3O2S(1-)*Na(1+)

CH3O2S(1-)*Na(1+)

Conditions
ConditionsYield
In ethanol for 0.166667h; Heating;A 95%
B 100%
sodium ethanolate
141-52-6

sodium ethanolate

2-(2-Methyl-propane-2-sulfonyl)-pyridine 1-oxide
109277-65-8

2-(2-Methyl-propane-2-sulfonyl)-pyridine 1-oxide

A

2-ethoxylpyridine N-oxide
3445-09-8

2-ethoxylpyridine N-oxide

B

C4H9O2S(1-)*Na(1+)

C4H9O2S(1-)*Na(1+)

Conditions
ConditionsYield
In ethanol for 0.25h; Heating;A n/a
B 100%
sodium ethanolate
141-52-6

sodium ethanolate

exo-7-carbethoxy-endo-9-methyl-2-oxabicyclo<4.3.1>decan-3-one
82979-09-7

exo-7-carbethoxy-endo-9-methyl-2-oxabicyclo<4.3.1>decan-3-one

(1S,2S,4R,5S)-2-(2-Ethoxycarbonyl-ethyl)-4-hydroxy-5-methyl-cyclohexanecarboxylic acid ethyl ester
82979-10-0

(1S,2S,4R,5S)-2-(2-Ethoxycarbonyl-ethyl)-4-hydroxy-5-methyl-cyclohexanecarboxylic acid ethyl ester

Conditions
ConditionsYield
In ethanol at 0℃; for 0.5h;100%
sodium ethanolate
141-52-6

sodium ethanolate

2-(Octane-1-sulfonyl)-pyridine 1-oxide
109277-64-7

2-(Octane-1-sulfonyl)-pyridine 1-oxide

A

2-ethoxylpyridine N-oxide
3445-09-8

2-ethoxylpyridine N-oxide

B

C8H17O2S(1-)*Na(1+)

C8H17O2S(1-)*Na(1+)

Conditions
ConditionsYield
In ethanol for 0.5h; Heating;A n/a
B 100%
sodium ethanolate
141-52-6

sodium ethanolate

(3-hexadecyloxysulfonyl-propyl)-trimethyl-ammonium; perchlorate

(3-hexadecyloxysulfonyl-propyl)-trimethyl-ammonium; perchlorate

ethyl hexadecyl ether
13933-61-4

ethyl hexadecyl ether

Conditions
ConditionsYield
In ethanol at 25℃; for 48h;100%
sodium ethanolate
141-52-6

sodium ethanolate

2-(4-benzyl-1-piperazinyl)-4-chloro-5,6,7,8-tetrahydroquinazoline
79051-10-8

2-(4-benzyl-1-piperazinyl)-4-chloro-5,6,7,8-tetrahydroquinazoline

2-(4-Benzyl-piperazin-1-yl)-4-ethoxy-5,6,7,8-tetrahydro-quinazoline
81532-51-6

2-(4-Benzyl-piperazin-1-yl)-4-ethoxy-5,6,7,8-tetrahydro-quinazoline

Conditions
ConditionsYield
In ethanol for 6h; Heating;100%
sodium ethanolate
141-52-6

sodium ethanolate

2,4,6-trichloro-1H-1,5,2λ5-diazaphosphorine 2-oxide
155932-10-8

2,4,6-trichloro-1H-1,5,2λ5-diazaphosphorine 2-oxide

4,6-dichloro-2-ethoxy-1H-1,5,2λ5-diazaphosphorine 2-oxide

4,6-dichloro-2-ethoxy-1H-1,5,2λ5-diazaphosphorine 2-oxide

Conditions
ConditionsYield
In benzene for 0.5h; Ambient temperature;100%
sodium ethanolate
141-52-6

sodium ethanolate

2-(p-methoxyphenyl)-1,3-diphenylbenzothiophenium perchlorate

2-(p-methoxyphenyl)-1,3-diphenylbenzothiophenium perchlorate

C29H26O2S

C29H26O2S

Conditions
ConditionsYield
In ethanol for 12h; Heating;100%
sodium ethanolate
141-52-6

sodium ethanolate

[6-Hydroxy-2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)chroman-5-yl]methyl bromide
187806-29-7

[6-Hydroxy-2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)chroman-5-yl]methyl bromide

5-ethyloxymethyl-γ-tocopherol
19741-08-3

5-ethyloxymethyl-γ-tocopherol

Conditions
ConditionsYield
In ethanol; hexane at 0℃; for 1h;100%
sodium ethanolate
141-52-6

sodium ethanolate

(+/-)-5,6-dimethyl-3a,4,7,7a-tetrahydro-2,1-oxathiaindene 1,1-dioxide

(+/-)-5,6-dimethyl-3a,4,7,7a-tetrahydro-2,1-oxathiaindene 1,1-dioxide

sodium 3,4-dimethyl-6-ethoxymethyl-3-cyclohexene-1-sulfonate

sodium 3,4-dimethyl-6-ethoxymethyl-3-cyclohexene-1-sulfonate

Conditions
ConditionsYield
Ambient temperature;100%
for 4h; Ambient temperature;100%
sodium ethanolate
141-52-6

sodium ethanolate

(+/-)-endo-4,3-oxathiatricyclo<5.2.1.02,6>deca-8-ene 3,3-dioxide

(+/-)-endo-4,3-oxathiatricyclo<5.2.1.02,6>deca-8-ene 3,3-dioxide

sodium 3-ethoxymethylbicyclo<2.2.1>hept-5-ene-2-sulfonate

sodium 3-ethoxymethylbicyclo<2.2.1>hept-5-ene-2-sulfonate

Conditions
ConditionsYield
Ambient temperature;100%
for 4h; Ambient temperature;100%
sodium ethanolate
141-52-6

sodium ethanolate

ethylene dibromide
106-93-4

ethylene dibromide

para-thiocresol
106-45-6

para-thiocresol

(2-ethoxyethyl)-para-thiocresol
57023-03-7

(2-ethoxyethyl)-para-thiocresol

Conditions
ConditionsYield
Stage #1: para-thiocresol With sodium ethanolate In ethanol at 20℃; Metallation;
Stage #2: ethylene dibromide In ethanol at 20℃; Alkylation;
Stage #3: sodium ethanolate In ethanol Substitution; Heating;
100%
sodium ethanolate
141-52-6

sodium ethanolate

methyldibromobismuth(III)
60458-17-5

methyldibromobismuth(III)

methyldiethoxybismutane
60458-07-3

methyldiethoxybismutane

Conditions
ConditionsYield
In ethanol 2 h, 20°C;100%
cis-3-phenyl-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester

cis-3-phenyl-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester

sodium ethanolate
141-52-6

sodium ethanolate

trans-3-phenyl-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester

trans-3-phenyl-piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-ethyl ester

Conditions
ConditionsYield
In ethanol for 4h; Heating / reflux;100%
2,2,2-trichloro-1-(4,5,6,7-tetrahydro-1H-indol-2-yl)ethanone
1346672-30-7

2,2,2-trichloro-1-(4,5,6,7-tetrahydro-1H-indol-2-yl)ethanone

sodium ethanolate
141-52-6

sodium ethanolate

4,5,6,7-tetrahydro-1H-indole-2-carboxylic acid ethyl ester
65880-18-4

4,5,6,7-tetrahydro-1H-indole-2-carboxylic acid ethyl ester

Conditions
ConditionsYield
In ethanol at 20℃; for 1h; Inert atmosphere;100%
With ethanol at 20℃; for 1h; Inert atmosphere;100%
In ethanol at 20℃; for 1h; Inert atmosphere;100%
1-(4-fluoro-phenyl)-4-iodo-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid[4-(2-phenyl-furo[3,2-b]pyridin-7-yloxy)-phenyl]-amide
1360906-01-9

1-(4-fluoro-phenyl)-4-iodo-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid[4-(2-phenyl-furo[3,2-b]pyridin-7-yloxy)-phenyl]-amide

sodium ethanolate
141-52-6

sodium ethanolate

4-ethoxy-1-(4-fluoro-phenyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid[4-(2-phenyl-furo[3,2-b]pyridin-7-yloxy)-phenyl]-amide
1360906-05-3

4-ethoxy-1-(4-fluoro-phenyl)-2-oxo-1,2-dihydro-pyridine-3-carboxylic acid[4-(2-phenyl-furo[3,2-b]pyridin-7-yloxy)-phenyl]-amide

Conditions
ConditionsYield
With ethanol In tetrahydrofuran at 20℃; for 1h; Sealed tube; Inert atmosphere;100%
ethanol
64-17-5

ethanol

ethyl 7-methyl-2-(methylsulfanyl)-4-oxo-3-(2-oxo-2-phenylethyl)-5-(2,2,2-trifluoroethoxy)-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-6-carboxylate
1269119-25-6

ethyl 7-methyl-2-(methylsulfanyl)-4-oxo-3-(2-oxo-2-phenylethyl)-5-(2,2,2-trifluoroethoxy)-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-6-carboxylate

sodium ethanolate
141-52-6

sodium ethanolate

ethyl 2-ethoxy-7-methyl-4-oxo-3-(2-oxo-2-phenylethyl)-5-(2,2,2-trifluoroethoxy)-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-6-carboxylate
1269119-28-9

ethyl 2-ethoxy-7-methyl-4-oxo-3-(2-oxo-2-phenylethyl)-5-(2,2,2-trifluoroethoxy)-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidine-6-carboxylate

Conditions
ConditionsYield
In tetrahydrofuran at 10 - 35℃; for 4h;100%
C24H29F2NPPd

C24H29F2NPPd

sodium ethanolate
141-52-6

sodium ethanolate

C26H33FNOPPd

C26H33FNOPPd

Conditions
ConditionsYield
In ethanol; benzene at 20℃; for 0.1h;100%
ethanol
64-17-5

ethanol

sodium ethanolate
141-52-6

sodium ethanolate

methanesulfonic acid 3-nitrobenzylester

methanesulfonic acid 3-nitrobenzylester

1-(ethoxymethyl)-3-nitrobenzene
80171-39-7

1-(ethoxymethyl)-3-nitrobenzene

Conditions
ConditionsYield
for 17h; Reflux; Inert atmosphere;100%
5-ethyl-1,3-diphenylimidazo[4,5-b]pyrazin-3-ium tetrafluoroborate

5-ethyl-1,3-diphenylimidazo[4,5-b]pyrazin-3-ium tetrafluoroborate

sodium ethanolate
141-52-6

sodium ethanolate

2-ethoxy-5-ethyl-1,3-diphenyl-2H-imidazo[4,5-b]pyrazine

2-ethoxy-5-ethyl-1,3-diphenyl-2H-imidazo[4,5-b]pyrazine

Conditions
ConditionsYield
In ethanol for 0.75h; Inert atmosphere; Cooling with ice;100%
3-(3,5-dimethyiphenyl)-1-phenyl-5-(trifluoromethoxy)benzimidazol-3-ium chloride

3-(3,5-dimethyiphenyl)-1-phenyl-5-(trifluoromethoxy)benzimidazol-3-ium chloride

sodium ethanolate
141-52-6

sodium ethanolate

3-(3,5-dimethylphenyl)-2-ethoxy-1-phenyl-5-(trifluoromethoxy)-2H-benzimidazole

3-(3,5-dimethylphenyl)-2-ethoxy-1-phenyl-5-(trifluoromethoxy)-2H-benzimidazole

Conditions
ConditionsYield
In n-heptane for 0.5h; Inert atmosphere;100%
2,4-dinitrobromobenzene
584-48-5

2,4-dinitrobromobenzene

sodium ethanolate
141-52-6

sodium ethanolate

2,4-dinitro-1-ethoxybenzene
610-54-8

2,4-dinitro-1-ethoxybenzene

Conditions
ConditionsYield
In ethanol at 25℃; Kinetics;100%
1-iodo-2,4-dinitrobenzene
709-49-9

1-iodo-2,4-dinitrobenzene

sodium ethanolate
141-52-6

sodium ethanolate

2,4-dinitro-1-ethoxybenzene
610-54-8

2,4-dinitro-1-ethoxybenzene

Conditions
ConditionsYield
In ethanol at 25℃; Kinetics;100%
5-bromo-2-chloro-3-methylpyridine
29241-60-9

5-bromo-2-chloro-3-methylpyridine

sodium ethanolate
141-52-6

sodium ethanolate

5-bromo-2-ethoxy-3-methylpyridine

5-bromo-2-ethoxy-3-methylpyridine

Conditions
ConditionsYield
Stage #1: 5-bromo-2-chloro-3-methylpyridine With sodium hydride In tetrahydrofuran; ethanol; mineral oil at 20℃; for 72.5h;
Stage #2: sodium ethanolate In tetrahydrofuran; ethanol; mineral oil Reflux;
100%
1-azido-3-fluoro-2-nitrobenzene
874279-84-2

1-azido-3-fluoro-2-nitrobenzene

sodium ethanolate
141-52-6

sodium ethanolate

C8H8N2O3

C8H8N2O3

Conditions
ConditionsYield
Stage #1: 1-azido-3-fluoro-2-nitrobenzene In toluene for 5h; Reflux;
Stage #2: sodium ethanolate In ethanol; toluene at 20℃; for 0.5h;
100%
3,5-difluoro-2-nitrophenylazide

3,5-difluoro-2-nitrophenylazide

sodium ethanolate
141-52-6

sodium ethanolate

4,6-diethoxybenzofuroxan

4,6-diethoxybenzofuroxan

Conditions
ConditionsYield
Stage #1: 3,5-difluoro-2-nitrophenylazide In toluene for 15h; Reflux;
Stage #2: sodium ethanolate In ethanol; toluene at 20℃; for 0.5h;
100%
5-bromo-2-chloro-3-nitropyridine
67443-38-3

5-bromo-2-chloro-3-nitropyridine

sodium ethanolate
141-52-6

sodium ethanolate

5-bromo-2-ethoxy-3-nitropyridine
886372-76-5

5-bromo-2-ethoxy-3-nitropyridine

Conditions
ConditionsYield
In ethanol at 75℃; for 1h;100%
In ethanol at 80℃; for 1h;57.67%

141-52-6Related news

Improving the Quality of the Quartz Fiber Postcore Bond Using Sodium ethoxide (cas 141-52-6) Etching and Combined Silane/Adhesive Coupling09/30/2019

The influence of different silane/dentin adhesives on the microtensile bond strengths of a hybrid composite to sodium ethoxide-etched quartz fiber posts was investigated. A prehydrolyzed silane was applied without an adhesive and compared to two-component systems in which hydrolysis of the silan...detailed

141-52-6Relevant articles and documents

Enhanced vapor-phase processing in fluorinated Fe4 single-molecule magnets

Rigamonti, Luca,Piccioli, Marco,Malavolti, Luigi,Poggini, Lorenzo,Mannini, Matteo,Totti, Federico,Cortigiani, Brunetto,Magnani, Agnese,Sessoli, Roberta,Cornia, Andrea

, p. 5897 - 5905 (2013)

A new tetrairon(III) single-molecule magnet with enhanced volatility and processability was obtained by partial fluorination of the ancillary β-diketonato ligands. Fluorinated proligand Hpta = pivaloyltrifluoroacetone was used to assemble the bis(alkoxido

Scavenging Reaction of Solvated Electron Produced by UV Laser from Iodide Anion in Liquid Beam

Matsumura, Hisashi,Mafune, Fumitaka,Kondow, Tamotsu

, p. 5861 - 5864 (1995)

A sodium iodide (NaI) solution in ethanol was introduced into vacuum as a continuous liquid flow (liquid beam) and irradiated with a 220 nm UV laser.Cluster cations containing ethoxide such as Na+(NaOEt), Na+(NaI)n(NaOEt) (n = 1-4), and Na+(NaI)n(NaOEt)2 (n = 1-4) were observed by a time-of-flight (TOF) mass spectrometer.Furthermore, addition of NH4+ or n-BuOH into the NaI ethanol solution resulted in suppressing the intensities of the peaks associated with these cluster ions.It is concluded that the ethoxide is produced by a scavenging reaction of a solvated electron with an ethanol molecule, and the reaction of the ethoxide formation competes with a scavenging reaction by NH4+ or n-BuOH.The rate equations of these competing processes predict the dependence of the ethoxide formation on the concentration of NH4+ or n-BuOH.Similar reaction products were observed from alcohol solutions of several iodides.

Synthesis of new polysubstituted (pyrazoles, pyrimidines and quinolines) five and six-membered heterocycles: Reaction of α,α-dioxoketene dithioacetals with nucleophiles

Ebraheem,Lokanatha Rai,Kudva.n,Bahjat

, p. 3486 - 3492 (2010)

A novel synthesis of polysubstituted pyrazoles 3a-d, pyrimidines 4a-f and quinolines 5a-c via the reaction of α,α-oxoketene dithioacetals 2a-c with hydrazine hydrate, malonohydrazide, urea, thiourea and aniline is reported and the synthetic potential of the method is demonstrated. The structure of the new compounds was established upon their elemental analysis, IR, 1H NMR and 13C NMR.

Iron(ii) complexes of 2,6-di(1H-pyrazol-3-yl)-pyridine derivatives with hydrogen bonding and sterically bulky substituents

Roberts, Thomas D.,Little, Marc A.,Kershaw Cook, Laurence J.,Halcrow, Malcolm A.

, p. 7577 - 7588 (2014)

Syntheses of 2,6-di(5-aminopyrazol-3-yl)pyridine (L1), 2,6-di(5-tertbutylcarboxamidopyrazol-3-yl)pyridine (L2), 2,6-di(5-tertbutylpyrazol-3-yl)pyridine (L3), 2-(5-tertbutylpyrazol- 3-yl)-6-(5-methylpyrazol-3-yl)pyridine (L4) and 2-(5- tertbutylpyrazol-3-yl)-6-(5-aminopyrazol-3-yl)pyridine (L5) are reported. Iron complex salts of the first four ligands were crystallographically characterised. The structures exhibit intermolecular hydrogen bonding between the cations and the anions and/or solvent, leading to a fluorite (flu) net, a 1D ladder structure, and a homochiral self-penetrating helical network related to the (10,3)-a (srs) topology. All the complexes are high-spin in the crystal, and bulk samples are also fully or predominantly high-spin at room temperature and below although two of the dried materials exhibit partial spin-state transitions on cooling. This journal is the Partner Organisations 2014.

The AAAA?DDDD hydrogen bond dimer. Synthesis of a soluble sulfurane as AAAA domain and generation of a DDDD counterpart

Taubitz, Joerg,Luening, Ulrich

, p. 1550 - 1555 (2009)

Sulfurane 5b with solubility enhancing substituents has been synthesized to be used as an AAAA recognition site in quadruple hydrogen bond heterodimers. A complementary DDDD partner [4b + H+] has been generated from a DDAD domain 4b by protonation. The association constant for the heterodimer complex formation has been determined by NMR titration in chloroform. CSIRO 2009.

Crystal structure of sodium ethoxide (C2H5ONa), unravelled after 180 years

Beske, Maurice,Tapmeyer, Lukas,Schmidt, Martin U.

, p. 3520 - 3523 (2020)

As early as 1837, Liebig synthesised solid C2H5ONa. Today, C2H5ONa is one of the standard bases in organic synthesis. Here, we report the identification of different solid phases and the crystal structures and p

Substituent dependence on the spin crossover behaviour of mononuclear Fe(ii) complexes with asymmetric tridentate ligands

Saiki, Ryo,Miyamoto, Haruka,Shiga, Takuya,Oshio, Hiroki,Sagayama, Hajime,Kumai, Reiji,Newton, Graham N.

, p. 3231 - 3236 (2019)

Three mononuclear iron(ii) complexes of the formula [FeII(H2L1-3)2](BF4)2·x(solv.) (H2L1-3 = 2-[5-(R-phenyl)-1H-pyrazole-3-yl] 6-benzimidazole pyridine; H2L1: R = 4-methylphenyl, H2L2, R = 2,4,6-trimethylphenyl, H2L3, R = 2,3,4,5,6-pentamethylphenyl) (1, H2L1; 2, H2L2; 3, H2L3) with asymmetric tridentate ligands (H2L1-3) were synthesized and their structures and magnetic behaviour investigated. Significant structural distortions of the dihedral angles between phenyl and pyrazole groups were observed and found to depend on the nature of the substituent groups. Cryomagnetic studies reveal that 1 and 2 show gradual spin crossover behavior, while 3 remains in the high spin state between 1.8 and 300 K.

Synthesis and characterization of new 5,5′-dimethyl- and 5,5′-diphenylhydantoin-conjugated hemorphin derivatives designed as potential anticonvulsant agents

Georgieva, Stela,Peneva, Petia,Rangelov, Miroslav,Tchekalarova, Jana,Todorov, Petar,Todorova, Nadezhda

, p. 2198 - 2217 (2022/02/16)

Herein, the synthesis and characterization of some novel N-modified hybrid analogues of hemorphins containing a C-5 substituted hydantoin residue as potential anticonvulsants and for the blockade of sodium channels are presented. Their structure-property relationships are highlighted by electrochemical and Fourier transform infrared spectroscopy (FT-IR) analysis methods. The lipophilicity and molecular docking of voltage-gated sodium channels were also determined. The new series of 5,5′-dimethyl- and 5,5′-diphenylhydantoin-conjugated hemorphin derivatives were obtained as C-terminal amides via solid-phase peptide synthesis, an Fmoc-strategy using 2-(1H-benzotriazole-1-yl)-1,1,3,3-tetramethylaminium tetrafluoroborate (TBTU). The anticonvulsant activity of the hybrid-peptides (0.25, 0.5 and 1 μg) was tested by maximal electroshock (MES) and 6 Hz psychomotor seizure tests using male ICR mice. None of the compounds tested showed neurotoxicity in the rotarod test. The reference drug phenytoin was used as a positive control. The most active compound Ph-5 showed 100% efficacy against the 6 Hz-induced psychomotor seizures at a dose of 1.0 μg and tonic seizures in the MES test at a lower dose of 0.5 μg. This analogue of VV-hemorphin-5 contained a 5,5′-diphenylhydantoin residue at the N-terminus and a hydrophobic Val-Val-Tyr-Pro-Trp-Thr-Gln-CONH2 amino acid sequence of the peptide molecule. The quantitative data for the 6 Hz test demonstrated that the peptide Ph-5 exhibited a median effective dose (ED50) value of 0.358 μg and PI >13.97, and ED50 of 0.25 μg and PI >20.35 in the MES test, respectively. Results from the docking study suggest that the neuropeptide Ph-5 is a potent inhibitor of sodium channels, and blockade of voltage-gated sodium channels could be the mechanism of action of the hybrid-peptide derivatives with anticonvulsant activity.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 141-52-6