39971-61-4

Basic information

• Product Name: salbutamol sulfate
• Synonyms: 1,3-Benzenedimethanol, a1-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, sulfate (1:1) (salt) (9CI);4-(2-(tert-Butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol sulfate
• CAS NO: 39971-61-4
• Molecular Formula: 2C₁₃H₂₁NO₃*H₂O₄S
• Molecular Weight: 0
• Mol File: 39971-61-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: salbutamol sulfate(CAS DataBase Reference)
• NIST Chemistry Reference: salbutamol sulfate(39971-61-4)
• EPA Substance Registry System: salbutamol sulfate(39971-61-4)

Safety Data

• Hazardous Substances Data: 39971-61-4(Hazardous Substances Data)

Downstream Products

• 324000-05-7 (R)-2-tert-butylamino-1-(4-hydroxy-2-hydroxymethyl-phenyl)ethanol 
• 324000-05-7 (S)-2-tert-butylamino-1-(4-hydroxy-2-hydroxymethyl-phenyl)ethanol 
• 4199-09-1 (S)-1-isopropylamino-3-(1-naphthyloxy)-2-propanol 
• 525-66-6 (R)-propranolol 

Relevant articles and documents

Process for the enantiomeric enrichment of salbutamol and salbutamol precursors

The present invention relates to a process for the enantiomeric enrichment of salbutamol and salbutamol precursors and the acid-addition salts thereof: where R is hydrogen or benzyl, R' is hydrogen or benzyl and X is CH2OH or COO-C1-C4-alkyl the process comprising the crystallization of a compound of the formula I in the form of its acid-addition salt with an achiral carboxylic acid A that has at least three carbon atoms and a solubility of less than 50 g/l in water at pH 3, 20°C and 1013 mbar, from a solution containing a mixture of the enantiomers of the compound of formula I and the achiral carboxylic acid A in the presence of seed crystals of the desired enantiomer of the compound of formula I or the acid addition salt thereof, whereby the enantiomerically enriched acid-addition salt of the compound of formula I is obtained.

Drug delivery system

A drug delivery system in which a taste masked solid is suspended in a liquid carrier. The solid has been rendered hydrophillic and its density approximates that of the carrier liquid.