400827-64-7 Usage
Uses
Used in Pharmaceutical Applications:
7 β aMino 3 [4 pyridyl 2 thiazole sulfur radical ] 3 cepheM 4 carboxylic acid ·2HCl is used as an active pharmaceutical ingredient for the development of new drugs. Its unique structure allows it to interact with specific biological targets, potentially leading to the treatment of various diseases.
Used in Chemical Synthesis:
In the chemical industry, 7 β aMino 3 [4 pyridyl 2 thiazole sulfur radical ] 3 cepheM 4 carboxylic acid ·2HCl can be used as a starting material or intermediate in the synthesis of other complex organic compounds. Its sulfur radical and carboxylic acid group provide opportunities for further functionalization and modification.
Used in Research and Development:
7 β aMino 3 [4 pyridyl 2 thiazole sulfur radical ] 3 cepheM 4 carboxylic acid ·2HCl can also be utilized in research and development settings, where it can serve as a probe or tool to study various biological processes and interactions. Its unique properties may help researchers gain insights into the mechanisms of certain diseases or the behavior of specific biological systems.
Used in Analytical Chemistry:
7 β aMino 3 [4 pyridyl 2 thiazole sulfur radical ] 3 cepheM 4 carboxylic acid ·2HCl can be employed as a reagent or standard in analytical chemistry for the detection, quantification, or identification of other compounds. Its distinct chemical properties may enable the development of new analytical methods or techniques.
Check Digit Verification of cas no
The CAS Registry Mumber 400827-64-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,0,8,2 and 7 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 400827-64:
(8*4)+(7*0)+(6*0)+(5*8)+(4*2)+(3*7)+(2*6)+(1*4)=117
117 % 10 = 7
So 400827-64-7 is a valid CAS Registry Number.
400827-64-7Relevant articles and documents
A cephalosporin nucleus lorraine ester intermediates preparation method
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Paragraph 0061; 0062; 0068; 0073, (2018/04/02)
The invention provides a preparation method of ceftaroline fosamil intermediate parent nucleus, which comprises the following steps: 3-hydroxycephem and an activation reagent are reacted under existence condition of an acid binding agent and an organic solvent to obtain an activated intermediate; the activation reagent comprises p-toluene sulfonyl chloride, benzenesulfonyl choride, 4-nitrobenzene sulfonyl chloride, trifluoroactic anhydride or trifluoromethanesulfonic anhydride; the activated intermediate and 4-(4-pyridyl)-2-mercaptothiazole are reacted, then is reacted to a quaternized reagent to obtain pyridinium salt; and then deprotection is carried out to obtain the ceftaroline fosamil intermediate parent nucleus. Compared with the prior art, The p-toluene sulfonyl chloride, benzenesulfonyl choride, 4-nitrobenzene sulfonyl chloride, trifluoroactic anhydride or trifluoromethanesulfonic anhydride are used for substituting the usage of a severe toxicity material, reaction security is increased, due to increasing steric hindrance of an activating group, rate for generating a delta-3 isomer is reduced, and purity and yield of the reaction products are increased.
CEPHALOSPORIN INTERMEDIATE AND PROCESS FOR ITS PREPARATION
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Page/Page column 20; 21; 22, (2016/09/22)
Provided is a synthesis of cephalosporin derivatives, characterized by the use of the new intermediates for the preparation of cephalosporin derivatives, a crystalline toluene hemi-solvate of benzhydryl (6R,7R)-7β-[(phenylacetyl)amino]-3-[4-pyridyl-2-thia
