401816-16-8 Usage
Uses
Used in Organic Synthesis:
2,6-Difluoropyridine-4-boronic acid is used as a reagent in the Suzuki-Miyaura cross-coupling reaction, a widely employed method for forming carbon-carbon bonds. Its versatile reactivity and functional group compatibility make it a valuable component in the synthesis of complex organic molecules.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2,6-Difluoropyridine-4-boronic acid serves as a key intermediate for the development of new drugs. Its unique structure and reactivity allow for the creation of novel bioactive compounds with potential therapeutic applications.
Used in Drug Development:
2,6-Difluoropyridine-4-boronic acid has potential applications in the development of new drugs and agrochemicals. Its ability to form stable carbon-carbon bonds and its compatibility with various functional groups make it a promising candidate for the synthesis of innovative pharmaceuticals and agrochemicals with improved efficacy and selectivity.
Used in the Pharmaceutical Industry:
In the pharmaceutical industry, 2,6-Difluoropyridine-4-boronic acid is used as a building block for the synthesis of various bioactive molecules. Its unique structure and reactivity enable the development of new drugs with improved pharmacological properties, such as increased potency, selectivity, and reduced side effects.
Used in the Agrochemical Industry:
In the agrochemical industry, 2,6-Difluoropyridine-4-boronic acid is utilized for the development of new agrochemicals, such as pesticides and herbicides. Its versatile reactivity and functional group compatibility contribute to the creation of novel compounds with enhanced performance and selectivity, leading to more effective and environmentally friendly agricultural solutions.
Check Digit Verification of cas no
The CAS Registry Mumber 401816-16-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,0,1,8,1 and 6 respectively; the second part has 2 digits, 1 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 401816-16:
(8*4)+(7*0)+(6*1)+(5*8)+(4*1)+(3*6)+(2*1)+(1*6)=108
108 % 10 = 8
So 401816-16-8 is a valid CAS Registry Number.
401816-16-8Relevant articles and documents
Substituted pyridines
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Page/Page column 5, (2008/06/13)
A class of 2,4-; 2,3,4-; 2,4,6-; 2,3,4,5,6-substituted pyridines is provided which include novel compounds. The substitutions are achieved according to methods disclosed herein in which a metallated pyridine is reacted with an electrophile. Suitable electrophiles include CO2, SO2, dialkylcarbonates, ureas, formamides, amides, carboxylic acid esters, mono- and dihaloalkyls, halogens such as chlorine, fluorine, bromine, and iodine, metallic salts, sulfones, sulfonyls, aldehydes, ketones, anhydrides, nitrites, and electrophilic boron compounds including, but not limited to, boron trialkoxides and boron trihalides. The subject invention more specifically discloses a process for the synthesis of 2,6-difluoropyridin-4-ylboronic acid which comprises: (1) reacting 2,4,6-trifluoropyridine with hydrazine monohydrate to produce 2,6-difluoro-4-hydrazinopyridine, (2) reacting the 2,6-difluoro-4-hydrazinopyridine with elemental bromine to produce 4-bromo-2,6-difluoropyridine, and (3) reacting the 4-bromo-2,6-difluoropyridine with an organolithium compound and a borate at a temperature of less than about 0° C. to produce the 2,6-difluoropyridin-4-ylboronic acid, wherein said process is conducted in an organic solvent.
Heterocyclic derivatives
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, (2008/06/13)
The invention relates to heterocyclic derivatives of the formula I wherein R1, A1, Z1, n, A2, Z2, Q1, Q2, Q3 and L have the meaning given in claim 1 and to their use as components of liquid crystalline media for electro-optical displays.
