403672-07-1Relevant articles and documents
Highly efficient biocatalytic resolution of cis- and trans-3-aminoindan-1- ol: Syntheses of enantiopure orthogonally protected cis- and trans-indane-1,3-diamine
Lopez-Garcia, Monica,Alfonso, Ignacio,Gotor, Vicente
, p. 3006 - 3014 (2007/10/03)
The efficient chemoenzymatic synthesis of enantiopure 1,3-difunctionalized indane derivatives has been achieved. The corresponding cis and trans N-protected amino alcohols were successfully resolved by acetylation using lipase B, which is a biocatalyst is
3-amino-1-indanole, method of synthesizing the same and method of optical resolution
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, (2008/06/13)
The present invention relates to a compound which is expected to be a synthetic intermediate for medicines and pesticides or a separating agent for chromatography or a enantiomerically resolving agent for racemic bodies. That is, it provides 3-amino-1-indanol represented by the formula (I), a process for synthesizing it, an enantiomerically active compound of 3-amino-1-indanol and a process for enantiomerically resolving 3-amino-1-indanol, and a separating agent for enantiomeric isomers comprising enantiomerically active compound thereof as an effective ingredient. In the formula, the configuration between OH group and NH2group are cis-configuration or trans-configuration and the compound may be a racemic body or an enantiomerically active compound.
